Evidence map›Paper›PMID 40397373›Full record

ReviewCurrent reviews in musculoskeletal medicine2025

Outcomes after Surgical Management of Large Joint Manifestations in Ehlers Danlos Syndrome and Hypermobility Conditions in Sports Medicine: a Systematic Review.

Caitlin Svendsen, Prushoth Vivekanantha, Doris Braunstein, Sneha Raja, Vireshwar Jagdeo, Andrew Duong, Nicole Simunovic, Olufemi R Ayeni

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Current reviews in musculoskeletal medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Caitlin SvendsenDivision of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, ON, Canada.
Prushoth VivekananthaDivision of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, ON, Canada.
Doris BraunsteinSchool of Medicine, University College Dublin, Dublin, Ireland.
Sneha RajaDivision of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, ON, Canada.
Vireshwar JagdeoDivision of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, ON, Canada.
Andrew DuongDivision of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, ON, Canada.
Nicole SimunovicDivision of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, ON, Canada.
Olufemi R AyeniDivision of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, ON, Canada. ayenif@mcmaster.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewJoint hypermobility can increase complications in surgical management of musculoskeletal conditions. The purpose of this review is to 1) summarize clinical outcomes in patients undergoing various Orthopedic sports medicine surgical procedures by joint, and 2) compare outcomes in patients with and without hypermobility. RECENT

findingsA total of 38 studies consisting of 144,609 patients and 144,860 joints were included (140,625 shoulders, 2,043 hips, 1,499 knees, 689 ankles, and four elbows). Notable heterogeneity exists within the literature regarding outcomes in hypermobile patients undergoing Orthopedic sports medicine procedures. In general, outcomes for hypermobile patients undergoing procedures of the shoulder, elbow, hip, and knee demonstrated similar or slightly worse outcomes across various patient reported outcomes measures (PROMs) and in terms of recurrent instability or dislocation. There were consistently worse outcomes (e.g. higher rates of post-operative recurrent instability, PROMs) in studies evaluating hypermobile patients undergoing surgery for chronic lateral ankle instability (CLAI) compared to non-hypermobile controls. Patients with joint hypermobility tend to have similar or worse outcomes following Orthopedic sports medicine procedures related to the shoulder, knee, hip, and elbow, and consistently worse outcomes for the ankle. Future studies are encouraged to focus on the effect of hypermobility on elbow and wrist sports pathologies.

Indexed as

Ehlers Danlos Syndrome (EDS)Generalized ligamentous laxityJoint hypermobilitySports proceduresSurgical outcomes

Identifiers

PMID40397373
PMCPMC12325825

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.