Evidence map›Paper›PMID 40397278›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2026

3D In Vitro Culture of Early Mouse Embryos and Trophoblast Tissue Explants.

Devila Prit, Shashank Jaitly, Niraimathi Govindasamy, Adrian Ranga, Ivan Bedzhov

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Devila PritEmbryonic Self-Organization Research Group, Max Planck Institute for Molecular Biomedicine, Münster, Germany.
Shashank JaitlyEmbryonic Self-Organization Research Group, Max Planck Institute for Molecular Biomedicine, Münster, Germany.
Niraimathi GovindasamyEmbryonic Self-Organization Research Group, Max Planck Institute for Molecular Biomedicine, Münster, Germany.
Adrian RangaLaboratory of Bioengineering and Morphogenesis, Department of Mechanical Engineering, KU Leuven, Leuven, Belgium. adrian.ranga@kuleuven.be.
Ivan BedzhovEmbryonic Self-Organization Research Group, Max Planck Institute for Molecular Biomedicine, Münster, Germany. ivan.bedzhov@mpi-muenster.mpg.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cellular dynamics during peri-implantation embryogenesis and the concurrent interactions at the embryo-maternal interface are inherently difficult to study due to intrauterine development in mammals. To model certain aspects of these processes in vitro, we have generated a biomimetic environment resembling the mechanical properties of the murine uterine stroma. Here we describe a step-by-step methodology for 3D culture of mouse embryos and ectoplacental cone explants in synthetic hydrogels that allow ex utero trophoblast invasion.

Indexed as

Cell Culture Techniques, Three DimensionalEmbryo Culture TechniquesEmbryo, MammalianTrophoblastsAnimalsBlastocystEmbryo ImplantationEmbryonic DevelopmentFemaleHydrogelsMicePregnancyHydrogels3D cultureBlastocystEctoplacental coneEgg cylinderHydrogelImplantationInvasionMouse embryoTrophoblastTrophoblast giant cells

Identifiers

PMID40397278

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.