Evidence map›Paper›PMID 40397131›Full record

ArticleTechnology in cancer research & treatment

Comparison of Deep Learning-Based Auto-Segmentation Results on Daily Kilovoltage, Megavoltage, and Cone Beam CT Images in Image-Guided Radiotherapy.

Zhixing Wang, Chengyu Shi, Carson Wong, Seyi M Oderinde, William T Watkins, Kun Qing, Bo Liu, Terence M Williams, An Liu, Chunhui Han

Abstract readComparative Study
In one paragraph

Article in Technology in cancer research & treatment. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zhixing WangDepartment of Radiation Oncology, City of Hope, Duarte, CA, USA.
Chengyu ShiDepartment of Radiation Oncology, City of Hope, Duarte, CA, USA.
Carson WongDepartment of Radiation Oncology, City of Hope, Duarte, CA, USA.
Seyi M OderindeRefleXion Medical, Hayward, CA, USA.
William T WatkinsDepartment of Radiation Oncology, City of Hope, Duarte, CA, USA.
Kun QingDepartment of Radiation Oncology, City of Hope, Duarte, CA, USA.
Bo LiuDepartment of Radiation Oncology, City of Hope, Duarte, CA, USA.ORCID 0000-0001-5696-5360
Terence M WilliamsDepartment of Radiation Oncology, City of Hope, Duarte, CA, USA.
An LiuDepartment of Radiation Oncology, City of Hope, Duarte, CA, USA.ORCID 0000-0002-8903-5028
Chunhui HanDepartment of Radiation Oncology, City of Hope, Duarte, CA, USA.ORCID 0000-0002-3717-8473

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IntroductionThis study aims to evaluate auto-segmentation results using deep learning-based auto-segmentation models on different online CT imaging modalities in image-guided radiotherapy.MethodsPhantom studies were first performed to benchmark image quality. Daily CT images for sixty patients were retrospectively retrieved from fan-beam kilovoltage CT (kVCT), kV cone-beam CT (kV-CBCT), and megavoltage CT (MVCT) scans. For each imaging modality, half of the patients received CT scans in the pelvic region, while the other half in the thoracic region. Deep learning auto-segmentation models using a convolutional neural network algorithm were used to generate organs-at-risk contours. Quantitative metrics were calculated to compare auto-segmentation results with manual contours.ResultsThe auto-segmentation contours on kVCT images showed statistically significant difference in Dice similarity coefficient (DSC), Jaccard similarity coefficient, sensitivity index, inclusiveness index, and the 95

Indexed as

Cone-Beam Computed TomographyDeep LearningImage Processing, Computer-AssistedNeoplasmsRadiotherapy, Image-GuidedRadiotherapy Planning, Computer-AssistedAlgorithmsFemaleHumansMaleOrgans at RiskRetrospective StudiesTomography, X-Ray Computedartificial intelligenceauto-segmentationdeep learningkV-CBCTkVCTMVCT

Identifiers

PMID40397131
PMCPMC12099101

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.