Evidence map›Paper›PMID 40397015›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Perovskite-Graphene Heterostructure Biosensor Integrated with Biotunable Nanoplasmonic Ternary Logic Gate for Ultrasensitive Cytokine Detection.

Jiaxing Sun, Lin Zhou, Zening Li, Guolin He, Hongju Mao, Jianlong Zhao, John A Hunt, Xianfeng Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jiaxing SunSchool of Science and Technology, Nottingham Trent University, Nottingham, NG11 8NS, UK.
Lin ZhouKey Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai, 200050, China.ORCID https://orcid.org/0000-0001-6892-0485
Zening LiKey Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai, 200050, China.
Guolin HeGeneral Surgery Center, Department of Hepatobiliary Surgery II, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, 510280, China.
Hongju MaoKey Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai, 200050, China.ORCID https://orcid.org/0000-0003-1613-1032
Jianlong ZhaoKey Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai, 200050, China.
John A HuntMedical Technologies Innovation Facility, Nottingham Trent University, Nottingham, NG11 8NS, UK.
Xianfeng ChenSchool of Science and Technology, Nottingham Trent University, Nottingham, NG11 8NS, UK.ORCID https://orcid.org/0000-0001-7091-1414

Funding

European Union's H2020 Marie Skłodowska-Curie Actions 872049National Key Research and Development Program of China 2023YFC2605100National Key Research and Development Program of China 2023YFC2605101National Natural Science Foundation of China 62231025Science and Technology Commission of Shanghai Municipality 21JM0010402Science and Technology Commission of Shanghai Municipality 22ZR1473500Science and Technology Program of Guangzhou 2024B03J0022
6 · The paper itself

Abstract

The integration of 2D-materials and optoelectronic devices has attracted great attention for advanced applications. We propose the first perovskite/graphene heterostructure-based FET biosensor with uniquely biotunable ternary logic gating functionality. The biosensor integrates a lateral perovskite-on-graphene heterostructure phototransistor with a vertical bio-nano-photonic filter, with a decoupled construction inset. In the phototransistor, photoactive perovskite quantum dots (PQDs) serve as sensitizers to absorb light while a high mobility single-layer graphene (SLG) acts as an expressway for carrier transport. In the bio-nano-photonic filter, a localized surface plasmon resonance (LSPR) is induced by gold nanoparticles (AuNPs) in conjunction with antigen-antibody binding, tuning the delivery of light passing through the filter and facilitating biotunable functionality with ternary modes. The biosensor is set up to detect human interleukin-6 (IL6) in order to determine and achieve ultrahigh sensitivity with a limit of detection (LOD) of 0.9 fg mL

Indexed as

Biosensing TechniquesCalcium CompoundsCytokinesGraphiteInterleukin-6OxidesTitaniumGoldHumansLimit of DetectionMetal NanoparticlesQuantum DotsSurface Plasmon ResonanceCalcium CompoundsCytokinesGoldGraphiteInterleukin-6OxidesperovskiteTitanium2D materialsbiosensorcytokineFETgrapheneheterostructureLSPRperovskiteternary logic gate

Identifiers

PMID40397015
PMCPMC12362746

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.