Evidence map›Paper›PMID 40397008›Full record

ArticleJournal of neuromuscular diseases2025

Exploring self-management of diet and physical activity in

Natasha Lervaag Welland, Benedicte Hagen Venås, Mari Ellefsen-Martinsen, Hanne Ludt Fossmo, Andreas Dybesland Rosenberger, Helene Dahl, Kristin Ørstavik, Marianne Nordstrøm

Abstract read
In one paragraph

Article in Journal of neuromuscular diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Lifestyle and dietary measures in Periodic Paralyses.Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Natasha Lervaag WellandFrambu Resource Centre for Rare Disorders (Frambu), Siggerud, Norway.ORCID 0009-0000-1929-9389
Benedicte Hagen VenåsFrambu Resource Centre for Rare Disorders (Frambu), Siggerud, Norway.ORCID 0009-0009-5797-7836
Mari Ellefsen-MartinsenFrambu Resource Centre for Rare Disorders (Frambu), Siggerud, Norway.ORCID 0009-0002-0338-3441
Hanne Ludt FossmoFrambu Resource Centre for Rare Disorders (Frambu), Siggerud, Norway.ORCID 0009-0003-4955-1057
Andreas Dybesland RosenbergerNational Neuromuscular Centre Norway (NMK), University Hospital of North Norway, Tromsø, Norway.ORCID 0009-0009-8228-4070
Helene DahlPatient Organization Representative, The Neuromuscular Disorders Association of Norway (NMD Norway), Nesbru, Norway.ORCID 0000-0002-6871-9826
Kristin ØrstavikSection for Rare Neuromuscular Disorders and Unit for Congenital and Hereditary Neuromuscular Disorders (EMAN), Department of Neurology, Oslo University Hospital, Oslo, Norway.ORCID 0000-0001-7900-7093
Marianne NordstrømFrambu Resource Centre for Rare Disorders (Frambu), Siggerud, Norway.ORCID 0000-0001-6327-2052

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHypokalemic Periodic Paralysis (HypoPP) is a rare genetic neuromuscular disorder characterized by attacks of skeletal muscle weakness or paralysis with spontaneous recovery. The attacks are frequently triggered by specific factors, and previous studies have identified certain associated lifestyle factors, such as dietary intake and physical activity. However, there is currently no in-dept knowledge on how patients experience and self-manage triggering factors in their everyday life.

objectiveIn this study, we aimed to explore patients' experiences with dietary intake and physical activity through semi-structured interviews. The research question was: Which strategies do individuals with HypoPP utilize in relation to dietary intake and physical activity to prevent or self-manage attacks of muscle weakness and paralysis?

methodsThe study included 14 participants aged 21-58 years with HypoPP due to abnormalities in calcium channel function caused by pathogenic variants in the

resultsThe participants experienced that regular meals with controlled portions of complex carbohydrates, limited intake of simple carbohydrates, engaging in regular mild to moderate exercise combined with warm-up and cool-down, and avoiding physical inactivity made them less vulnerable to attacks of muscle weakness and paralysis. Furthermore, participants highlighted the cumulative effect of triggers, by consistently reporting feeling more susceptible to attacks when exposed to multiple triggers simultaneously.

conclusionsThe participants experienced self-management through dietary modifications and adjustments in physical activity to reduce symptoms in

Indexed as

DietExerciseHypokalemic Periodic ParalysisSelf-ManagementAdultCalcium Channels, L-TypeFemaleHumansMaleMiddle AgedQualitative ResearchYoung AdultCACNA1S protein, humanCalcium Channels, L-Typecomplex-carbohydratesdietary intakeexercisehypokalemic periodic paralysisinactivitylifestylephysical activitysimple-carbohydrates

Identifiers

PMID40397008
PMCPMC13142878

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.