Evidence map›Paper›PMID 40396449›Full record

ArticleOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery2025

Dynamic Airway CT for Morphometric Analysis of Pediatric Tracheomalacia Throughout Respiration.

Hannah F Case, Michael Bindschadler, Michael Barbour, Tanya Meyer, John P Dahl, Seth D Friedman, Alberto Aliseda, Randall A Bly

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hannah F CaseDepartment of Otolaryngology-Head and Neck Surgery, University of Washington, Seattle, Washington, USA.ORCID https://orcid.org/0000-0003-4097-9500
Michael BindschadlerCenter for Respiratory Biology and Therapeutics, Seattle Children's Hospital, Seattle, Washington, USA.
Michael BarbourCenter for Respiratory Biology and Therapeutics, Seattle Children's Hospital, Seattle, Washington, USA.ORCID https://orcid.org/0000-0001-5160-0119
Tanya MeyerDepartment of Otolaryngology-Head and Neck Surgery, University of Washington, Seattle, Washington, USA.ORCID https://orcid.org/0000-0002-1112-2674
John P DahlDepartment of Pediatric Otolaryngology, Children's Mercy Kansas City, Kansas City, Missouri, USA.ORCID https://orcid.org/0000-0003-2728-3576
Seth D FriedmanCenter for Respiratory Biology and Therapeutics, Seattle Children's Hospital, Seattle, Washington, USA.ORCID https://orcid.org/0000-0001-8785-7215
Alberto AlisedaDepartment of Mechanical Engineering, University of Washington, Seattle, Washington, USA.ORCID https://orcid.org/0000-0002-5832-2999
Randall A BlyDepartment of Otolaryngology-Head and Neck Surgery, University of Washington, Seattle, Washington, USA.ORCID https://orcid.org/0000-0001-5308-527X

Funding

Clinician-Scientist Research Education and Training in OtolaryngologyR25DC021791 · NIDCD · UNIVERSITY OF WASHINGTON · PI Jay T. Rubinstein, Jennifer S. Stone · 2024 to 2026
$1.6M
NIDCD NIH HHS R25 DC021791
6 · The paper itself

Abstract

Dynamic airway computed topography (4D-CT) can be used to evaluate the trachea in pediatric patients with tracheomalacia. The 4D-CT enables objective and quantitative evaluation throughout all phases of respiration; however, current systems focus on qualitative review of generated 4D images. Few analytic workflows are available to assist in the extraction of the quantitative geomorphic data generated. In this study, we share a protocol developed within the 3D Slicer framework that performs semi-automatic tracheal segmentation and subsequent geomorphic analysis. This methodology is applied to 4 sample cases with varying degrees of tracheal collapse throughout all phases of respiration to demonstrate output of cross-sectional area, aspect ratio (defined as the ratio between minor-to-major luminal axis lengths), and tracheal volume (bound by the subglottis and carina) metrics.

Indexed as

Four-Dimensional Computed TomographyRespirationTracheaTracheomalaciaChildChild, PreschoolFemaleHumansInfantMaledynamic computed topographypediatric otolaryngologytracheomalaciaupper airway obstruction

Identifiers

PMID40396449
PMCPMC13162523

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.