Evidence map›Paper›PMID 40396340›Full record

ReviewSchizophrenia bulletin2025

From Idealist to Realist-Designing and Implementing Shared Decision-Making Interventions in the Choice of Antipsychotic Prescription in People Living with Psychosis (SHAPE): A Realist Review.

Ita Fitzgerald, Laura J Sahm, Ian Maidment, Emma Wallace, Yaara Zisman-Ilani, Mikkel Højlund, Sarah O'Dwyer, Ciara Ní Dhubhlaing, Erin K Crowley, Jo Howe

Abstract readReview
In one paragraph

Review in Schizophrenia bulletin, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ita FitzgeraldPharmacy Department, St Patrick's Mental Health Services, Dublin, Ireland.ORCID 0000-0002-9570-8823
Laura J SahmPharmaceutical Care Research Group, School of Pharmacy, University College Cork, Ireland.
Ian MaidmentSchool of Pharmacy, College of Health and Life Sciences, Aston University, United Kingdom.ORCID 0000-0003-4152-9704
Emma WallaceDepartment of General Practice, School of Medicine, University College Cork, Ireland.
Yaara Zisman-IlaniDepartment of Social & Behavioral Sciences, College of Public Health, Temple University, Philadelphia, PA, United States.
Mikkel HøjlundDepartment of Psychiatry Aabenraa, Mental Health Services Region of Southern Denmark, Aabenraa, Denmark.
Sarah O'DwyerDepartment of Medicine, St Patrick's Mental Health Services, Dublin, Ireland.
Ciara Ní DhubhlaingPharmacy Department, St Patrick's Mental Health Services, Dublin, Ireland.
Erin K CrowleyPharmaceutical Care Research Group, School of Pharmacy, University College Cork, Ireland.
Jo HoweSchool of Pharmacy, College of Health and Life Sciences, Aston University, United Kingdom.

Funding

Health Research Board of Ireland Emerging Clinician Scientist HRB ECSA 2020 002
6 · The paper itself

Abstract

backgroundShared decision-making (SDM) implementation remains limited in psychosis management, particularly within antipsychotic prescribing. When and why prescribers engage in SDM within these contexts is largely unknown. Part 1 of this two-part realist review aimed to understand the impact of structural and contextual factors on prescriber engagement in SDM within antipsychotic prescribing. STUDY

designCINAHL Plus, Cochrane Library, Embase, PsycINFO, PubMed, Scopus, Sociological Abstracts, Web of Science, and Google Scholar were searched for evidence to develop realist program theories outlining the relationship between macro-level contexts and their impact on prescriber behaviors. STUDY

resultsFrom 106 included documents, five program theories explaining relationships between (i) leadership and governance, (ii) workforce development, and (iii) service delivery contexts and their impact on reducing prescriber engagement with behaviors required of SDM application were developed. No facilitative macro-level contexts were identified. Key mechanisms reducing prescriber engagement in desired behaviors include fear of individual blame for adverse outcomes and exposure to liability, pressure from service environments to prioritize decreasing risk of harm, devaluing of experiential knowledge, and beliefs that SDM conflicts with duties of beneficence and non-maleficence.

conclusionEven empirically efficacious interventions will be difficult to implement at scale within real-world settings due to misalignment with complex cultural, legal, and professional realities prominent therein. Mechanisms responsible for reducing prescriber engagement in SDM should be the target of structural interventions necessary to support contextual integration into psychosis management. Part 2 outlines features of service delivery contexts, workforce development, and technology that can increase prescriber engagement in SDM.

Indexed as

Antipsychotic AgentsDecision Making, SharedPsychotic DisordersHumansAntipsychotic Agents

Identifiers

PMID40396340
PMCPMC12236316

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.