Evidence map›Paper›PMID 40396334›Full record

Trial reportThe International journal of eating disorders2025

Mechanisms of Change in Cognitive-Behavioral Therapy for Adults With Binge-Eating Disorder: A Dynamic Structural Equation Modeling Approach.

Ricarda Schmidt, Danielle Schewe, Stephan Herpertz, Stephan Zipfel, Brunna Tuschen-Caffier, Hans-Christoph Friederich, Andreas Mayr, Martina de Zwaan, Anja Hilbert

Abstract readRandomized Controlled TrialMulticenter Study
In one paragraph

Trial report in The International journal of eating disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ricarda SchmidtIntegrated Research and Treatment Center AdiposityDiseases, Behavioral Medicine Research Unit, Department of Psychosomatic Medicine and Psychotherapy, University of Leipzig Medical Center, Leipzig, Germany.ORCID 0000-0001-7794-2897
Danielle ScheweIntegrated Research and Treatment Center AdiposityDiseases, Behavioral Medicine Research Unit, Department of Psychosomatic Medicine and Psychotherapy, University of Leipzig Medical Center, Leipzig, Germany.ORCID 0009-0006-7237-1945
Stephan HerpertzDepartment of Psychosomatic Medicine and Psychotherapy, LWL-University, Bochum, Germany.
Stephan ZipfelPsychosomatic Medicine and Psychotherapy, Medical University Hospital Tuebingen, Tuebingen, Germany.ORCID 0000-0003-1659-4440
Brunna Tuschen-CaffierDepartment of Clinical Psychology and Psychotherapy, University of Freiburg, Freiburg, Germany.ORCID 0000-0002-2565-7792
Hans-Christoph FriederichDepartment of General Internal Medicine and Psychosomatics, Medical University Hospital Heidelberg, Heidelberg, Germany.
Andreas MayrInstitute for Medical Biometry and Statistics, Philipps-University Marburg, Marburg, Germany.ORCID 0000-0001-7106-9732
Martina de ZwaanDepartment of Psychosomatic Medicine and Psychotherapy, Hannover Medical School, Hannover, Germany.ORCID 0000-0002-7918-6957
Anja HilbertIntegrated Research and Treatment Center AdiposityDiseases, Behavioral Medicine Research Unit, Department of Psychosomatic Medicine and Psychotherapy, University of Leipzig Medical Center, Leipzig, Germany.ORCID 0000-0003-2775-1296

Funding

German Federal Ministry of Education and Research 01EO1501German Federal Ministry of Education and Research 01GV0601
6 · The paper itself

Abstract

objectiveCognitive-behavioral therapy (CBT) is the most well-established treatment for binge-eating disorder (BED), but the mechanisms of change remain poorly understood. This study investigated in CBT for BED the effects of overvaluation of shape and weight and dietary restraint on subsequent objective binge-eating episodes (OBEs).

methodIn a multicenter randomized-controlled trial, 84 patients diagnosed with full- or subsyndromal BED were offered 20 individual sessions of CBT over 4 months. Dynamic structural equation modeling (DSEM) was used to disentangle within- and between-patient associations of overvaluation of shape and weight, dietary restraint, and OBEs.

resultsBetween the first and last week of therapy, there were significant reductions in overvaluation of shape and weight, dietary restraint, and OBEs. DSEM showed significant within-patient effects of overvaluation of shape and weight on the subsequent number of OBEs. Weeks with lower overvaluation of shape and weight levels were followed by weeks with fewer OBEs. Although no within-patient effect of dietary restraint on OBEs was found, within-patient dietary restraint levels positively predicted subsequent overvaluation of shape and weight levels. DISCUSSION: The findings suggest that reductions in overvaluation of shape and weight may precede improvements in binge eating during CBT for BED, supporting its role as a potential mechanism of change. While dietary restraint did not show a direct temporal link to binge eating, its association with overvaluation points to a potential indirect role. These results underscore the value of targeting cognitive features of BED in CBT and highlight the need for more temporally sensitive assessments in mechanisms research.

Indexed as

Binge-Eating DisorderBody ImageCognitive Behavioral TherapyAdultFemaleHumansLatent Class AnalysisMaleMiddle AgedTreatment OutcomeYoung Adultbinge‐eating disordercognitive‐behavioral therapydietary restraintmechanisms of changeovervaluation of shape and weight

Identifiers

PMID40396334
PMCPMC12423583

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.