Evidence map›Paper›PMID 40396298›Full record

ArticleMovement disorders clinical practice2025

Association between Perceived Dysphagia Symptoms and Swallowing Physiology in Parkinson's Disease.

Rabab Rangwala, Mariana Mendes Bahia, Jing Song, Danny Bega, Bonnie Martin-Harris

Abstract read
In one paragraph

Article in Movement disorders clinical practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
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  3. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rabab RangwalaDepartment of Communication Sciences and Disorders, School of Communication, Northwestern University, Evanston, Illinois, USA.ORCID https://orcid.org/0000-0002-2617-7301
Mariana Mendes BahiaDepartment of Speech and Hearing Science, University of Illinois Urbana-Champaign, Champaign, Illinois, USA.
Jing SongDepartment of Preventive Medicine (Biostatistics), Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Danny BegaDepartment of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Bonnie Martin-HarrisDepartment of Communication Sciences and Disorders, School of Communication, Northwestern University, Evanston, Illinois, USA.

Funding

Research and Mentoring on Swallowing Impairment and Respiratory-Swallow CoordinatK24DC012801 · NIDCD · NORTHWESTERN UNIVERSITY · PI MARTIN-HARRIS, BONNIE J · 2013 to 2024
$1.8M
Michael J. Fox Foundation for Parkinson's Research MJFF-009650NIDCD NIH HHS K24 DC012801NIDCD NIH HHS NIH/NIDCD 2K24DC012801-0Northwestern University
6 · The paper itself

Abstract

backgroundSwallowing disorders are prevalent in Parkinson's disease (PD). Swallowing assessment often relies on patient-reported outcome measures (PROMs). Although PROMs and physiologic swallowing measures correlate with disease severity, the relationship between PROMs and physiologic swallowing impairments is unclear.

objectivesOur aim was to (1) delineate the relationship between perceived swallowing symptoms and physiologic swallowing impairments; and (2) determine the relationship between swallowing-related quality of life (QoL) and physiologic impairments.

methodsA total of 31 individuals with PD (mean age = 64.8, standard deviation = 9.4) and dysphagia were recruited. PROMs included the Sydney Swallow Questionnaire (SSQ) and Swallowing Quality of Life Survey (SWAL-QOL) to measure perceived swallowing-related symptoms and QoL, respectively. Participants underwent a Modified Barium Swallow Study (MBSS) to obtain physiologic swallowing measures, including the Modified Barium Swallow Impairment Profile (MBSImP) and Penetration-Aspiration Scale (PAS). Multiple linear regression analyses assessed the associations between PROMs and physiologic measures, controlling for disease duration.

resultsPerceived swallowing difficulties indicated mild to moderate symptoms (SSQ: 20-871.5), and perceived swallowing-related QoL showed moderate to no impact (SWAL-QOL: 52.5%-100%). Swallowing components oral residue (97%) and delayed pharyngeal swallow (97%) were the most frequently impaired on the MBSImP. Furthermore, 45.2% of participants showed airway invasion (PAS ≥3) in at least one swallow trial. Regression analysis showed significant associations between MBSImP pharyngeal total score with SSQ (P < 0.001, R

conclusionsThese findings suggest that PROMs may not fully capture all aspects of physiological swallowing impairments. Relying solely on PROMs may overlook critical swallowing deficits not perceived by the patient, highlighting the need for objective swallowing assessments in PD.

Indexed as

DeglutitionDeglutition DisordersParkinson DiseaseAgedFemaleHumansMaleMiddle AgedPatient Reported Outcome MeasuresQuality of LifeSeverity of Illness IndexSurveys and Questionnairesdysphagiamodified barium swallow impairment profileParkinson's diseasepatient‐reported outcome measuresswallowing

Identifiers

PMID40396298
PMCPMC12528960

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.