Evidence map›Paper›PMID 40396181›Full record

ArticleFrontiers in immunology2025

Vitamin D inhibits apoptosis in THP-1 cells infected with mycobacterium tuberculosis through TNF signaling pathway.

Yusheng Yang, Jiezhong Deng, Pan Liu, Jinyue He, Jiulin Tan, Bo Yu, Yun Bai, Fei Luo, Jianzhong Xu, Zehua Zhang

Abstract read
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The role of vitamin D signalling in β cell apoptosis: a systematic review.Apoptosis : an international journal on programmed cell death · 2026
    Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yusheng Yang *Department of Orthopedic, Southwest Hospital, Army Medical University, Chongqing, China.
Jiezhong Deng *Department of Orthopedic, Southwest Hospital, Army Medical University, Chongqing, China.
Pan LiuDepartment of Orthopedic, Southwest Hospital, Army Medical University, Chongqing, China.
Jinyue HeDepartment of Orthopedic, Southwest Hospital, Army Medical University, Chongqing, China.
Jiulin TanDepartment of Orthopedic, Southwest Hospital, Army Medical University, Chongqing, China.
Bo YuDepartment of Orthopedic, Southwest Hospital, Army Medical University, Chongqing, China.
Yun BaiInstitute of Orthopedic Trauma of Chinese People's Liberation Army (PLA), The 80th Group Army Hospital, Weifang, Shandong, China.
Fei LuoDepartment of Orthopedic, Southwest Hospital, Army Medical University, Chongqing, China.
Jianzhong XuDepartment of Orthopedic, Southwest Hospital, Army Medical University, Chongqing, China.
Zehua ZhangDepartment of Orthopedic, Southwest Hospital, Army Medical University, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin D (VD) has been extensively associated with the resistance against tuberculosis (TB); however, the mechanism underlying the reduction in TB susceptibility by VD remains uncertain. In our prior investigation, we discovered the relationship between VD and

Indexed as

ApoptosisMycobacterium tuberculosisSignal TransductionTuberculosisTumor Necrosis Factor-alphaVitamin DAnimalsFemaleHumansInterleukin-6MaleReceptors, CalcitriolReceptors, Tumor Necrosis Factor, Type ITHP-1 CellsInterleukin-6Receptors, CalcitriolReceptors, Tumor Necrosis Factor, Type ITumor Necrosis Factor-alphaVDR protein, humanVitamin DapoptosisinflammationMycobacterium tuberculosisTNFvitamin D

Identifiers

PMID40396181
PMCPMC12089043

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.