Evidence map›Paper›PMID 40396124›Full record

ArticleFrontiers in molecular biosciences2025

Exploring focal adhesion data: dynamic parameter extraction from FRAP and FLAP experiments using chemical master equation.

Luciana Renata de Oliveira, Matheus Gimenez Fernandes, José Salvatore Leister Patane, Jean-Marc Schwartz, José Eduardo Krieger, Christoph Ballestrem, Ayumi Aurea Miyakawa

Abstract read
In one paragraph

Article in Frontiers in molecular biosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Luciana Renata de Oliveira *Laboratório de Genetica e Cardiologia Molecular, Instituto do Coração (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brazil.
Matheus Gimenez Fernandes *Laboratório de Genetica e Cardiologia Molecular, Instituto do Coração (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brazil.
José Salvatore Leister PataneLaboratório de Genetica e Cardiologia Molecular, Instituto do Coração (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brazil.
Jean-Marc SchwartzSchool of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.
José Eduardo KriegerLaboratório de Genetica e Cardiologia Molecular, Instituto do Coração (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brazil.
Christoph Ballestrem *Manchester Cell-Matrix Centre, Division of Cell-Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.
Ayumi Aurea Miyakawa *Laboratório de Genetica e Cardiologia Molecular, Instituto do Coração (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The dynamic behavior of proteins within cellular structures can be studied using fluorescence recovery after photobleaching (FRAP) and fluorescence loss after photobleaching (FLAP) experiments. These techniques provide insights into molecular mobility by estimating parameters such as turnover rates

Indexed as

chemical master equationFLAPfocal adhesionFRAPprotein dynamicsprotein interaction

Identifiers

PMID40396124
PMCPMC12088951

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.