ArticleAutophagy reports2022
DRAMs and autophagy: a family affair.
Article in Autophagy reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Bridging the Gap between Sequence and Structure Classifications of Proteins with AlphaFold Models.Journal of molecular biology · 2024Article
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Macroautophagy/autophagy is a conserved catabolic process that delivers intracellular materials to lysosomes for degradation. This process promotes cell survival by maintaining cellular homeostasis and supplying substrates to produce energy during nutrient-deprived conditions. DRAM1 (DNA damage regulated autophagy modulator 1) is involved in DNA-damage-induced autophagy and belongs to an evolutionarily conserved protein family, which contains five members in human. Our recent study provides the initial characterization of the last two members of the DRAM family in autophagy regulation. Our findings revealed that TMEM150C/DRAM4 (transmembrane protein 150C) and TMEM150A/DRAM5 are nutrient-responsive members of the DRAM family that manifest interconnected roles in modulating the autophagic flux and cell survival under nutrient-deprived conditions. Abbreviations: DRAM1: DNA damage regulated autophagy modulator 1 EBSS: Earle's balanced salt solution MAP1LC3/LC3: Microtubule associated protein 1 light chain 3.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.