Evidence map›Paper›PMID 40395934›Full record

ReviewFrontiers in cell and developmental biology2025

A tale of Rabs and the exocyst complex in ciliary trafficking and biogenesis.

Priyanka Upadhyai, Debalina Bose, Neha Quadri

Abstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Ciliary Membrane Lipid Homeostasis in Health and Disease.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Priyanka UpadhyaiDepartment of Medical Genetics, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Debalina BoseAdvanced Technology Development Centre, Indian Institute of Technology Kharagpur, Kharagpur, West Bengal, India.
Neha QuadriDepartment of Medical Genetics, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The primary cilium is a microtubule-based sensory cell organelle templated by a modified parent centriole that mediates mechanotransduction and response to biochemical cues such as morphogens to regulate organismal development and homeostasis. Given that the cilium is a specialized microdomain devoid of its translation machinery, it relies on the endomembrane pathway for the delivery of proteins and other biomolecules to it. This review provides a comprehensive insight into how membrane trafficking modulators such as Rab and Rab-like proteins, and the exocyst complex control transport to the primary cilia, in turn regulating various aspects of their assembly and function. We integrate findings from

Indexed as

ciliary traffickingciliopathiesexocystprimary ciliaRab-like proteinsRabs

Identifiers

PMID40395934
PMCPMC12089063

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.