Evidence map›Paper›PMID 40395908›Full record

ArticleArchives of medical science : AMS2025

MicroRNA let-7f protects against H

Kuo Li, Zhan-Qiang Wang, Jun-Ling Zhang, Pei-Yuan Lv

Abstract read
In one paragraph

Article in Archives of medical science : AMS, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kuo LiDepartment of Neurology, Hebei Medical University, Shijiazhuang, Hebei, China.
Zhan-Qiang WangDepartment of Neurology, Hebei Medical University, Shijiazhuang, Hebei, China.
Jun-Ling ZhangDepartment of Neurology, Cangzhou Central Hospital, Shijiazhuang , Hebei, China.
Pei-Yuan LvDepartment of Neurology, Hebei Medical University, Shijiazhuang, Hebei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Alzheimer's disease (AD) is the leading cause of dementia in late adult life. Emerging evidence shows that microRNAs (miRNAs) play vital roles in the pathogenesis of AD. The aim of the present study was to elucidate the underlying role of miR-let-7f in oxidative damage in SH-SY5Y cells. Material and methods: miRNA microarray analysis was performed to detect the miRNAs' differential expression in AD patients and normal elderly volunteers. Cell injury was evaluated on the basis of cell viability and apoptosis. The effect of miR-let-7f on H Results: MiR-let-7f was overexpressed in AD patients. When exposed to H Conclusions: The up-regulation of miR-let-7f alleviated the H

Indexed as

AKT-2Alzheimer’s diseasemicroRNAmiR-let-7foxidative damage

Identifiers

PMID40395908
PMCPMC12087342

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.