Evidence map›Paper›PMID 40395861›Full record

ArticleMechanobiology in medicine2024

Extracellular matrix stiffness modulates the mechanophenotypes and focal adhesions of colon cancer cells leading to their invasions via YAP1.

Kaide Xia, Wenhui Hu, Yun Wang, Jin Chen, Zuquan Hu, Chenyi An, Pu Xu, Lijing Teng, Jieheng Wu, Lina Liu and 3 more

Abstract read
In one paragraph

Article in Mechanobiology in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Harnessing mechanobiology to enhance cell therapy.Mechanobiology in medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Kaide XiaSchool of Basic Medical Sciences/School of Biology & Engineering, Guizhou Medical University, Guiyang, 550025, PR China.
Wenhui HuSchool of Basic Medical Sciences/School of Biology & Engineering, Guizhou Medical University, Guiyang, 550025, PR China.
Yun WangSchool of Basic Medical Sciences/School of Biology & Engineering, Guizhou Medical University, Guiyang, 550025, PR China.
Jin ChenSchool of Basic Medical Sciences/School of Biology & Engineering, Guizhou Medical University, Guiyang, 550025, PR China.
Zuquan HuSchool of Basic Medical Sciences/School of Biology & Engineering, Guizhou Medical University, Guiyang, 550025, PR China.
Chenyi AnSchool of Basic Medical Sciences/School of Biology & Engineering, Guizhou Medical University, Guiyang, 550025, PR China.
Pu XuSchool of Basic Medical Sciences/School of Biology & Engineering, Guizhou Medical University, Guiyang, 550025, PR China.
Lijing TengSchool of Basic Medical Sciences/School of Biology & Engineering, Guizhou Medical University, Guiyang, 550025, PR China.
Jieheng WuSchool of Basic Medical Sciences/School of Biology & Engineering, Guizhou Medical University, Guiyang, 550025, PR China.
Lina LiuSchool of Basic Medical Sciences/School of Biology & Engineering, Guizhou Medical University, Guiyang, 550025, PR China.
Sichao ZhangSchool of Basic Medical Sciences/School of Biology & Engineering, Guizhou Medical University, Guiyang, 550025, PR China.
Jinhua LongSchool of Basic Medical Sciences/School of Biology & Engineering, Guizhou Medical University, Guiyang, 550025, PR China.
Zhu ZengSchool of Basic Medical Sciences/School of Biology & Engineering, Guizhou Medical University, Guiyang, 550025, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Distal metastasis is the main cause of clinical treatment failure in patients with colon cancer. It is now known that the invasion and metastasis of cancer cells is precisely regulated by chemical and physical factors

Indexed as

Colon cancerECM stiffnessFocal adhesionsMechanophenotypesMetastasis

Identifiers

PMID40395861
PMCPMC12082314

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.