ArticleFrontiers in veterinary science2025
Insights into growth retardation and dwarfism caused by goose parvovirus in goslings: a transcriptomic profiling study.
Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Goose parvovirus (GPV) poses a significant threat to the waterfowl industry as it results in a high mortality rate and stunted growth in surviving goslings, leading to significant economic losses. We used 120 goslings and goose embryo fibroblasts inoculated with the GPV SYG61 strain to study the pathogenesis of GPV by pathological and gene expression profile changes. Fourteen days after infection with the GPV SYG61 strain, goslings showed a mortality rate of 63.33%, along with dwarfism, significant weight loss, and severe histopathological lesions in the liver and jejunum. Serum analysis revealed a marked increase in the levels of immunosuppressive factors such as TGF-
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