Evidence map›Paper›PMID 40395767›Full record

ArticleFrontiers in chemistry2025

Design, synthesis, and biological investigation of new thiazole-based derivatives as multi-targeted inhibitors endowed with antiproliferative, antioxidant, and antibacterial properties.

Hesham A M Gomaa, Asmaa M Atta, Mohamed E Shaker, Sami I Alzarea, Tariq G Alsahli, Eid Alatwi, Arafa Musa, Fatma A M Mohamed, Hayat Ali Alzahrani, Aliaa M Mohassab and 3 more

Abstract read
In one paragraph

Article in Frontiers in chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Design, synthesis,RSC advances · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hesham A M GomaaDepartment of Pharmacology, College of Pharmacy, Jouf University, Sakaka, Aljouf, Saudi Arabia.
Asmaa M AttaPharmaceutical Chemistry Department, Faculty of Pharmacy, Badr University in Cairo (BUC), Badr City, Cairo, Egypt.
Mohamed E ShakerDepartment of Pharmacology, College of Pharmacy, Jouf University, Sakaka, Aljouf, Saudi Arabia.
Sami I AlzareaDepartment of Pharmacology, College of Pharmacy, Jouf University, Sakaka, Aljouf, Saudi Arabia.
Tariq G AlsahliDepartment of Pharmacology, College of Pharmacy, Jouf University, Sakaka, Aljouf, Saudi Arabia.
Eid AlatwiDepartment of Pharmacology, College of Pharmacy, Jouf University, Sakaka, Aljouf, Saudi Arabia.
Arafa MusaDepartment of Pharmacognosy, College of Pharmacy, Jouf University, Sakaka, Aljouf, Saudi Arabia.
Fatma A M MohamedDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences at Al-Qurayyat, Jouf University, Al-Qurayyat, Saudi Arabia.
Hayat Ali AlzahraniApplied Medical Science College, Medical Laboratory Technology Department, Northern Border University, Arar, Saudi Arabia.
Aliaa M MohassabDepartment of Medicinal Chemistry, Faculty of Pharmacy, Minia University, Minia, Egypt.
Alshaimaa AbdelmoezDepartment of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt.
Stefan BräseInstitute of Biological and Chemical Systems, IBCS-FMS, Karlsruhe Institute of Technology, Karlsruhe, Germany.
Bahaa G M YoussifDepartment of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: A novel series of thiazole-based derivatives Methods: The structures of the new compounds Results and Discussion: Compounds

Indexed as

antibacterialanticancerantioxidantEGFRVEGFR-2

Identifiers

PMID40395767
PMCPMC12088962

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.