Evidence map›Paper›PMID 40395693›Full record

ArticleFrontiers in neuroscience2025

Race, diabetes, and cognitive function: a cross-sectional analysis of intersecting disparities in the NHANES cohort.

Lingling Wang, Qin Zhou, Yushuang Yin, Wenqi Zhang, Chen Wang, Guanwen Lin, Duozhi Wu, Zhihua Wang

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Article in Frontiers in neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Lingling Wang *Department of Anesthesiology, Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University), Haikou, China.
Qin Zhou *Department of Anesthesiology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Yushuang YinDepartment of Anesthesiology, Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University), Haikou, China.
Wenqi ZhangDepartment of Anesthesiology, Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University), Haikou, China.
Chen WangDepartment of Anesthesiology, Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University), Haikou, China.
Guanwen LinDepartment of Anesthesiology, Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University), Haikou, China.
Duozhi WuDepartment of Anesthesiology, Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University), Haikou, China.
Zhihua WangDepartment of Anesthesiology, Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University), Haikou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cognitive impairment poses a considerable challenge to public health systems worldwide, and its severity often varies depending on racial disparities. Diabetes, a prevalent chronic disease, is also known to adversely affect cognitive function. However, the interaction between race and diabetes in influencing cognitive function has not been well defined. This study aims to investigate the combined effects of race and diabetes on cognitive function using a demographically diverse group of elderly individuals. Methods: Data were drawn from the National Health and Nutrition Examination Survey (NHANES) from 2011 to 2014, involving a sample of 2,586 elderly participants aged 60 and above. Multivariate regression models were employed to assess the effects of race, diabetes status, and their interaction on cognitive test scores. Cognitive function was evaluated using the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) test, the Delayed Recall Test, the Animal Fluency Test (AFT), and the Digit Symbol Substitution Test (DSST). Results: Mexican Americans and Non-Hispanic Black people have the most frequent rates of diabetes. Non-Hispanic White people score the highest in all cognitive tests, while Mexican Americans and other Hispanics score the lowest ( Conclusion: This study found significant differences in diabetes prevalence and cognitive performance by race, along with a robust negative correlation between diabetes status and cognitive function. However, the interaction between race and diabetes does not significantly affect cognitive function.

Indexed as

cognitive functiondiabetesinteractionNHANESrace and ethnicity

Identifiers

PMID40395693
PMCPMC12089048

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.