Outcomes Following Implantation With Mesh Suture: A Registry of 1111 Patients.

Background: Mesh suture is a novel suture design intended to distribute pressure at the suture-tissue interface, potentially reducing suture pull-through and repair failures. This study aimed to evaluate the feasibility of mesh suture closures across surgical indications and assess early outcomes, with emphasis on abdominal wall closure. Methods: A registry was created using institutional implant logs from January 2023 to July 2024 across an integrated healthcare system. A retrospective chart review collected demographics, surgical details, and complications. Results: In total, 1111 patients received mesh suture by 86 surgeons. Most cases involved full-thickness abdominal wall closures (88.2%). Further analysis focused on abdominal wall closures without planar mesh (N = 862). The 90-day surgical site infection rate was 9.0%, and the surgical site event rate was 11.8%. There were 9 (1.0%) fascial dehiscence events, 3 (0.3%) chronic draining sinuses, and 2 (0.2%) enterocutaneous fistulae. The 90-day readmission and reoperation rates were 7.0% and 7.5%, respectively. The hernia formation rate was 4.8%. On univariate analysis, American Society of Anesthesiology class, wound class, and diabetes were significantly associated with major complications ( Conclusions: Mesh suture appears versatile and user-friendly across specialties and indications. Early outcomes are encouraging; however, prospective studies with longer follow-up are needed to further evaluate long-term performance.