Evidence map›Paper›PMID 40395612›Full record

ArticleFrontiers in endocrinology2024

Assessment of molecular and morphological dynamics during long-time

Wanxue Wang, Plamen Todorov, Evgenia Isachenko, Gohar Rahimi, Markus Merzenich, Nina Mallmann-Gottschalk, Yang Zhou, Jilong Yao, Xuemei Li, Volodimir Isachenko

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in endocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Research progress of ferroptosis in obesity and its complications.Journal of physiology and biochemistry · 2026
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wanxue WangDepartment of Obstetrics and Gynaecology, Medical Faculty, Cologne University, Cologne, Germany.
Plamen TodorovDepartment of Reproductive Biotechnology and Cryobiology of Gametes Institute of Biology and Immunology of Reproduction of Bulgarian Academy of Sciences (BAS), Sofia, Bulgaria.
Evgenia IsachenkoDepartment of Obstetrics and Gynaecology, Medical Faculty, Cologne University, Cologne, Germany.
Gohar RahimiDepartment of Obstetrics and Gynaecology, Medical Faculty, Cologne University, Cologne, Germany.
Markus MerzenichDepartment of Obstetrics and Gynaecology, Medical Faculty, Cologne University, Cologne, Germany.
Nina Mallmann-GottschalkDepartment of Obstetrics and Gynaecology, Medical Faculty, Cologne University, Cologne, Germany.
Yang ZhouDepartment of Obstetrics and Gynaecology, Medical Faculty, Cologne University, Cologne, Germany.
Jilong YaoReproductive Medicine Centre, Shenzhen Maternity and Child Healthcare Hospital, Shenzhen, China.
Xuemei LiReproductive Medicine Centre, Shenzhen Maternity and Child Healthcare Hospital, Shenzhen, China.
Volodimir IsachenkoDepartment of Obstetrics and Gynaecology, Medical Faculty, Cologne University, Cologne, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cryopreservation of human ovarian tissue is a technology for patients undergoing aggressive anticancer treatments. This technology includes the following stages: saturation by permeable cryoprotectants, freezing, thawing, removal of cryoprotectants, as well as tissues Objective: Evaluation of quality of tissue after cryopreservation and Methods: Ovarian tissue was frozen in 6% ethylene glycol and 6% dimethyl sulfoxide with speed of cooling 0.3°C/min and thawed at 100°C. After removal of cryoprotectants tissue fragments were Results: DNA and RNA analyses after cultivation indicated a rise in gene fusion and alternative splicing events, potentially affecting gene expression and cellular functions. Conclusion: Long-time

Indexed as

CryopreservationOvaryAdultCryoprotective AgentsFemaleHumansTissue Culture TechniquesCryoprotective Agentshuman ovarian tissue cryopreservationInsertions-Deletions (InDel)in vitro culturenegative effect on genes expressionprotein kinase inhibitor gamma (PKIG)SE (skipped exon)Single Nucleotide Polymorphism (SNP)

Identifiers

PMID40395612
PMCPMC12089959

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.