Evidence map›Paper›PMID 40395547›Full record

ArticleFrontiers in nutrition2025

Association between live microbe intake and severe headache or migraine: evidence from NHANES 1999-2004.

Rongjiang Xu, Xiangmin Yu, Ruonan Zhang, Xiaonuo Xu, Xiaoping Fan, Liang Dong, Jiying Zhou

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Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Rongjiang Xu *Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Xiangmin Yu *Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Ruonan ZhangDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Xiaonuo XuDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Xiaoping FanPhase I Clinical Research Center, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Liang DongDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Jiying ZhouDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The pathogenesis of migraine is not fully understood until now. This study was designed to explore whether the intake of live dietary microbes could be used as an auxiliary means for the treatment of severe headache and migraine. Methods: Data used in this study were came from the US National Health and Nutrition Examination Survey (NHANES) from 1999 to 2004. Participants were divided into three groups according to the dietary live microbe classification system, namely low, medium and high dietary live microbe groups. Weighted logistic regression models were used for statistical analysis. Results: A total of 13,443 participants were included in the present study. Compared with the low dietary live microorganism group, the migraine OR (95% CI) of medium-high dietary live microorganism group is 0.71 (0.63-0.81) and 0.73 (0.62-0.86), respectively, in the unadjusted model. After fully adjusting for confounding factors, patients in medium-high dietary live microbe group had a lower prevalence of migraine in contrast to those in low dietary live microbe group (Medium OR: 0.79, 95% CI: 0.68-0.93, Conclusion: Our study shows that a moderate-high intake of live dietary microbes is inversely associated with the prevalence of severe headache or migraine.

Indexed as

cross-sectional studydietary live microbemicrobiological therapyNHANESsevere headache or migraine

Identifiers

PMID40395547
PMCPMC12088940

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