ArticleRespirology case reports2025
Pulmonary Sarcomatoid Carcinoma Initially Misdiagnosed as Aspergillosis: A Diagnostic Challenge.
Article in Respirology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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1 author.
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Abstract
Pulmonary sarcomatoid carcinoma (PSC) is a rare and aggressive malignancy that often presents atypically, leading to incomplete diagnosis. We report a 55-year-old male with chronic obstructive pulmonary disease who presented with productive cough and haemoptysis. Initial bronchoscopy revealed fungal hyphae consistent with Aspergillus infection. The misleading clinical presentation led to an incomplete diagnosis. Subsequent lung biopsy and immunohistochemistry confirmed PSC harbouring an EGFR L858R mutation. Despite the presence of a targetable mutation, the patient showed a poor response to EGFR-targeted therapy. This case highlights the diagnostic challenges and therapeutic complexities when PSC coexists with an airway fungal infection.
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