ArticleEndoscopy international open2025
Red dichromatic imaging enhances submucosal visibility during endoscopic submucosal dissection: Pilot study.
Article in Endoscopy international open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Improvement in the Visibility of Submucosal Layers and Vessels with Amber-Red Color Imaging in Colorectal Endoscopic Submucosal Dissection.Digestive diseases and sciences · 2026Observational
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and study aims: In 2020, Olympus Medical Systems Corporation introduced red dichromatic imaging (RDI) as a novel image-enhanced endoscopy (IEE) technology. However, clinical evidence regarding its practical applications and the lesions for which RDI is beneficial remains limited. Endoscopic submucosal dissection (ESD) is an essential therapeutic option for gastrointestinal tumors, yet achieving clear visualization of the dissecting layer remains a significant challenge. This study aimed to evaluate the efficacy of RDI in enhancing visualization of the dissecting layer during ESD. Methods: A total of 86 images from 43 gastrointestinal tumors (esophagus, stomach, duodenum, colon, and rectum) were evaluated by eight endoscopists. Visibility of the dissecting layer was assessed using a scale ranging from -2 (poor) to 2 (excellent) under white light imaging (WLI) and RDI. In addition, the color difference between the submucosal and muscular layers was analyzed using the International Commission on Illumination Lab color space system. Results: RDI significantly improved visibility of the dissecting layer compared with WLI. Moreover, RDI showed a significantly greater color difference between the submucosal and muscular layers than WLI. Conclusions: RDI enhances visualization during ESD by improving visibility of the dissecting layer and increasing color differentiation compared with conventional WLI. These findings suggest that incorporating RDI into routine endoscopic practice could lead to more precise and efficient ESD procedures, ultimately improving patient outcomes.
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