Evidence map›Paper›PMID 40395256›Full record

ArticleCureus2025

Systemic Sclerosis in a Seven-Year-Old Girl Responding to Mycophenolate Mofetil: A Case Report.

Mohamed Alwadai, Hasan Almusaad, Rawan Yusuf, Rawah Almutawa, Shaikha Albanna

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mohamed AlwadaiPediatrics, Salmaniya Medical Complex, Manama, BHR.
Hasan AlmusaadPediatrics, Salmaniya Medical Complex, Manama, BHR.
Rawan YusufPediatrics, Salmaniya Medical Complex, Manama, BHR.
Rawah AlmutawaPediatrics, Salmaniya Medical Complex, Manama, BHR.
Shaikha AlbannaPediatrics, Salmaniya Medical Complex, Manama, BHR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Juvenile systemic sclerosis (JSSc) is a chronic, multisystem, connective tissue disease typically characterized by symmetrical fibrous thickening and hardening of the skin combined with fibrous changes in internal organs, such as the esophagus, intestinal tract, heart, lungs, and kidneys. We present the case of a seven-year-old female with a history of chest pain, irregular episodes of vomiting, and shortness of breath. Physical examination revealed hardening of the skin and darkish discoloration prominent on arms. Blood serology showed a positive anti-Scl-70 antibodies test, suggestive of JSSc. Treatment with prednisolone was initiated, followed by mycophenolate mofetil (MMF). This case highlights the importance of considering MMF in the treatment of patients with JSSc. Early diagnosis and intervention are essential in optimizing the quality of life for patients with JSSc.

Indexed as

chronic joint paindiffuse systemic sclerosislimited systemic sclerosispediatric rheumatologyprogressive dysphagia

Identifiers

PMID40395256
PMCPMC12091258

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.