ArticleCureus2025
Indocyanine Green and Radioisotope Tracers for Sentinel Lymph Node Mapping in Early-Stage Cervical Cancer: A Prospective Comparative Study.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Nuclear medicine in the operating room: present and future.The British journal of radiology · 2026Review
- Sentinel Lymph Node Mapping Compared with Selective Lymph Node Sampling in the Surgical Staging of Endometrial Cancer: A Prospective Observational Study.Diagnostics (Basel, Switzerland) · 2026Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aim The aim of this study is to compare the number and pattern of sentinel lymph nodes (SLNs) identified by indocyanine green (ICG) and radioisotope (RI) tracers in early-stage cervical cancer (CC) and evaluate the clinical implications of multiple SLN detections by ICG. Methods This prospective study included 88 patients with histologically confirmed CC who underwent semi-radical/radical hysterectomy or trachelectomy with SLN mapping using both ICG and RI tracers at a single tertiary center between April 2017 and December 2024. ICG was injected into the cervix immediately before surgery, and RI (99m technetium-phytate) was administered the day before surgery. SLNs were detected intraoperatively using near-infrared fluorescence and gamma-ray probes. SLN detection counts were compared bilaterally between the two tracers. Results The bilateral SLN detection rate was equivalent for both tracers (92.0%). However, ICG identified significantly more SLNs per patient than RI (mean: 2.56 vs. 2.10;
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Registered trials
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