Evidence map›Paper›PMID 40395224›Full record

ArticleMechanobiology in medicine2024

Low-magnitude high-frequency vibration reduces prostate cancer growth and extravasation

Amel Sassi, Kimberly Seaman, Xin Song, Chun-Yu Lin, Yu Sun, Lidan You

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Mechanobiology in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Amel SassiInstitute of Biomedical Engineering, University of Toronto, M5S 3G9, Canada.
Kimberly SeamanDepartment of Mechanical & Industrial Engineering, University of Toronto, M5S 3G9, Canada.
Xin SongDepartment of Mechanical & Industrial Engineering, University of Toronto, M5S 3G9, Canada.
Chun-Yu LinInstitute of Biomedical Engineering, University of Toronto, M5S 3G9, Canada.
Yu SunInstitute of Biomedical Engineering, University of Toronto, M5S 3G9, Canada.
Lidan YouInstitute of Biomedical Engineering, University of Toronto, M5S 3G9, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer (PCa) continues to rank among the most common malignancies in Europe and North America with significant mortality rates despite advancements in detection and treatment. Physical activity is often recommended to PCa patients due to its benefits in preventing disease recurrence and managing treatment-related side effects. However, physical activity may be challenging for elderly or bedridden patients. As such, vibration therapy has been proposed as a safe, effective, and easy to perform alternative treatment that may confer similar effects as physical exercise. Specifically, low-magnitude high frequency (LMHF) vibration has been shown to decrease breast cancer extravasation into the bone and reduce other types of cancer proliferation by impacting cell viability. Here, we investigated the effects of daily application of LMHF vibration (0.3 ​g, 60 ​Hz, 1 ​hour/day for 3 days) on prostate cancer growth and bone metastasis

Indexed as

Bone metastasisLow-magnitude high-frequency vibrationMechanical loadingMicrofluidicOsteocyteProstate cancerSpheroidVibration

Identifiers

PMID40395224
PMCPMC12082162

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.