Evidence map›Paper›PMID 40395214›Full record

ArticleMultivariate behavioral research

Three Approaches to Testing for Statistical Suppression.

Felix B Muniz, David P MacKinnon

Abstract read
In one paragraph

Article in Multivariate behavioral research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Felix B MunizCenter for Indigenous Health, Johns Hopkins University.
David P MacKinnonDepartment of Psychology, Arizona State University, Tempe, AZ, USA.

Funding

Estimating Mediation Effects in Prevention StudiesR37DA009757 · NIDA · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI MACKINNON, DAVID P · 2015 to 2024
$3.5M
NIDA NIH HHS R37 DA009757
6 · The paper itself

Abstract

Suppression effects are important for theoretical and applied research because these effects occur when there is an unexpected increase in an effect when it is adjusted for a third variable. This paper investigates three approaches to testing for statistical suppression. The first test was proposed in 1978 and is based on the relationship between the zero-order and semi-partial correlations. The second test comes from a condition that is necessary for suppression proposed in 1997. The third test is an extension of the test for the inconsistent mediated effect. We derive standard errors for the Velicer, and Sharpe and Roberts tests, conduct a statistical simulation study, and apply all three tests to two real data sets and several published correlation matrices. In the simulation study, the test based on inconsistent mediation had the best properties overall. For the data examples, when raw data were available, we constructed bootstrap confidence intervals to assess significance, and for correlations, we compared each test statistic to the normal distribution to assess statistical significance. Each test gave consistent results when applied to the example data sets. Analytical work demonstrated conditions where each test gave conflicting results. The mediation test of suppression based on the sign of the product of the mediated effect and the direct effect had the best overall performance.

Indexed as

Models, StatisticalComputer SimulationConfidence IntervalsData Interpretation, StatisticalHumansmediationregressionSuppression

Identifiers

PMID40395214
PMCPMC12301867

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.