Evidence map›Paper›PMID 40394989›Full record

ArticleEuropace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology2025

Diagnostic, pharmacological, and ablation approaches for idiopathic ventricular fibrillation: the 2024 European Heart Rhythm Association survey.

Giulio Conte, Andreas Metzner, Ante Anic, Laura Perrotta, Diego Penela, Julian Chun

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Article in Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Giulio ConteDivision of Cardiology, Cardiocentro Ticino Institute, Ente Ospedaliero Cantonale, via Tesserete 48, 6900 Lugano, Switzerland.ORCID 0000-0003-2248-3456
Andreas MetznerUniversity Heart and Vascular Center Hamburg-Eppendorf, Martinistraße 52, 20251 Hamburg, Germany.ORCID 0000-0002-6818-6396
Ante AnicDepartment for Cardiovascular Diseases, University Clinical Hospital Split, Split, Croatia.ORCID 0000-0002-6864-3999
Laura PerrottaArrhythmia Unit, University Hospital Careggi, EP Lab, Largo Brambilla 3, Florence 50134, Italy.ORCID 0000-0002-4322-1183
Diego PenelaArrhythmology Department, IRCCS Humanitas Research Hospital, Rozzano, Italy.ORCID 0009-0009-7221-4829
Julian ChunCardioangiologisches Centrum Bethanien, Agaplesion Markus Krankenhaus, Frankfurt, Germany.ORCID 0000-0002-2355-6015

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe aim of the European Heart Rhythm Association (EHRA) physician-based survey was to assess current clinical practice regarding the diagnostic assessment and therapeutic management of idiopathic ventricular fibrillation (IVF) across European Society of Cardiology (ESC) countries and to evaluate adherence to the 2022 ESC guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death. METHODS AND

resultsAn online 24-item was developed and disseminated by the Scientific Initatives Committee of EHRA. A total of 206 physicians from 41 countries completed the questionnaire. Respondents declaring a full diagnostic assessment of IVF, including at least coronary angiogram/cardiac computed tomography scan, electrocardiogram monitoring, exercise stress test, pharmacological challenges, and cardiac magnetic resonance, were 71 (35%). Cardiac magnetic resonance, sodium channel blocker test, and genetic testing were reported by 51, 34, and 43%, respectively. The most preferred first-line therapeutic strategy in case of recurrent implantable cardioverter-defibrillator (ICD) shocks was drug therapy (88%). In case of first-line strategy failure, the preferred reported strategy was ablation (53%).

conclusionThis survey highlights a significant heterogeneity of the diagnostic approach to IVF with underuse of crucial examinations. In line with guideline recommendation, drug therapy is more often considered as first-line therapy and ablation as second-line therapy for recurrent ICD shocks. However, quinidine is considered as drug of choice by <25% of respondents.

Indexed as

Anti-Arrhythmia AgentsCatheter AblationDeath, Sudden, CardiacElectric CountershockPractice Patterns, Physicians'Ventricular FibrillationDefibrillators, ImplantableEuropeFemaleGuideline AdherenceHealth Care SurveysHumansMalePractice Guidelines as TopicTreatment OutcomeAnti-Arrhythmia AgentsAblationDiagnosisEHRA surveyGenetic testingIdiopathic ventricular fibrillationSudden cardiac deathVentricular arrhythmias

Identifiers

PMID40394989
PMCPMC12092335

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.