Evidence map›Paper›PMID 40394749›Full record

ArticleSe pu = Chinese journal of chromatography2025

[Rapid identification and analysis of hemoglobin isoelectric focusing electrophoresis images based on deep learning].

Wei-Chen Ji, You-Li Tian, Hao-Dong Fu, Gen-Han Zha, Cheng-Xi Cao, Li Wei, Qiang Zhang

Abstract readEnglish Abstract
In one paragraph

Article in Se pu = Chinese journal of chromatography, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wei-Chen JiSchool of Electronic Information & Electrical Engineering,Shanghai Jiao Tong University,Shanghai 200240,China.
You-Li TianSchool of Electronic Information & Electrical Engineering,Shanghai Jiao Tong University,Shanghai 200240,China.
Hao-Dong FuCollege of Chemistry and Chemical Engineering,Hainan Normal University,Haikou 571158,China.
Gen-Han ZhaSchool of Electronic Information & Electrical Engineering,Shanghai Jiao Tong University,Shanghai 200240,China.
Cheng-Xi CaoSchool of Electronic Information & Electrical Engineering,Shanghai Jiao Tong University,Shanghai 200240,China.
Li WeiShanghai Sixth People's Hospital,Shanghai Jiao Tong University,Shanghai 200235,China.
Qiang ZhangSchool of Electronic Information & Electrical Engineering,Shanghai Jiao Tong University,Shanghai 200240,China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gel electrophoresis is used to separate and analyze macromolecules (such as DNA, RNA, and proteins) and their fragments, and highly reproducible and efficient automatic band-detection methods have been developed to analyze gel images. Uneven background, low contrast, lane distortion, blurred band edges, and geometric deformation pose detection-accuracy challenges during automatic band detection. In order to address these issues, various correction algorithms have been proposed; however, these algorithms rely on researcher experience to adjust and optimize parameters based on image characteristics, which introduces human error while qualitatively and quantitatively processing bands. Isoelectric focusing (IEF) gel electrophoresis separates proteins with high-resolution based on isoelectric point (pI) differences. Microarray IEF (mIEF) is used for the auxiliary diagnosis of diabetes and adult

Indexed as

Deep LearningHemoglobinsAlgorithmsHumansIsoelectric FocusingHemoglobinsband detectiondeep learninghemoglobin (Hb)isoelectric focusing (IEF) electrophoresismarker-free

Identifiers

PMID40394749
PMCPMC12093207

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.