Evidence map›Paper›PMID 40394742›Full record

ArticleSe pu = Chinese journal of chromatography2025

[Internal exposure characteristics and health risk assessment of organophosphate esters in urban residents].

Hua-Wei Wang, Shi-Yu Shi, Ling Liu, Ding Chen, Zhi-Xian Lyu, Zi-Yi Song, You-Jie Wang, Lu-Lu Song, Su-Rong Mei

Abstract readEnglish Abstract
In one paragraph

Article in Se pu = Chinese journal of chromatography, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hua-Wei WangHongshan District Center for Disease Control and Prevention,Wuhan 430070,China.
Shi-Yu ShiKey Laboratory of Environment & Health of Ministry of Education,Institute of Environmental Medicine,School of Public Health,Huazhong University of Science and Technology,Wuhan 430030,China.
Ling LiuKey Laboratory of Environment & Health of Ministry of Education,Institute of Environmental Medicine,School of Public Health,Huazhong University of Science and Technology,Wuhan 430030,China.
Ding ChenHongshan District Center for Disease Control and Prevention,Wuhan 430070,China.
Zhi-Xian LyuKey Laboratory of Environment & Health of Ministry of Education,Institute of Environmental Medicine,School of Public Health,Huazhong University of Science and Technology,Wuhan 430030,China.
Zi-Yi SongKey Laboratory of Environment & Health of Ministry of Education,Institute of Environmental Medicine,School of Public Health,Huazhong University of Science and Technology,Wuhan 430030,China.
You-Jie WangDepartment of Maternal and Child Health,School of Public Health,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China.
Lu-Lu SongDepartment of Maternal and Child Health,School of Public Health,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China.
Su-Rong MeiKey Laboratory of Environment & Health of Ministry of Education,Institute of Environmental Medicine,School of Public Health,Huazhong University of Science and Technology,Wuhan 430030,China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The contents of 15 organophosphate ester (OPE) metabolites in the urine of 1 869 adults residing in urban areas were quantified using ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). How gender, age, body mass index (BMI), smoking status, exercise frequency, family income and dietary intake affected the contents of OPE metabolites in human urine were discussed. Furthermore, the daily intake (EDI) of OPEs was evaluated based on the contents of OPE metabolites in urine. The corresponding potential non-carcinogenic risks were calculated in combination with the non-carcinogenic risk reference dose (RfD), with the health risks of individual OPE monomers and overall cumulative exposure expressed using the hazard quotient (HQ) and hazard index (HI). Six OPE metabolites exhibited detection frequencies in excess of 60%, with bis(2-butoxyethyl) phosphate (BBOEP) and 1-hydroxy-2-propyl bis(1-chloro-2-propyl) phosphate (BCIPHIPP), as the two main OPE metabolites, detected at levels of 0.56 and 0.36 ng/mL, respectively. Men exhibited higher urine contents of bis(1,3-dichloro-2-propyl) phosphate (BDCIPP), BCIPHIPP, and BBOEP than women, whereas women exhibited higher urine contents of 4-hydroxyphenyl-phenylphosphate (4-HO-DPHP). The levels of BCIPHIPP and diphenyl phosphate (DPHP) were found to correlate negatively with age, while the BCIPHIPP, and di-

Indexed as

Environmental ExposureEstersOrganophosphatesAdultAgedChromatography, High Pressure LiquidFemaleHumansMaleMiddle AgedRisk AssessmentTandem Mass SpectrometryUrban PopulationYoung AdultEstersOrganophosphatesexposure profileshealth risk assessmentinfluencing factorsorganophosphate esters (OPEs)urine

Identifiers

PMID40394742
PMCPMC12093206

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.