Evidence map›Paper›PMID 40394736›Full record

ArticleSe pu = Chinese journal of chromatography2025

[Quality control strategy for targeted quantitative analysis of chemical pollutants in China National Human Biomonitoring Program].

Yan-Wei Yang, Xu Zhang, Xiao Lin, Qi Sun, Hui Fu, Yi-Fu Lu, Tian Qiu, Zhuo-Na Zhang, Lin-Na Xie, Hai-Jing Zhang and 7 more

Abstract readEnglish Abstract
In one paragraph

Article in Se pu = Chinese journal of chromatography, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Yan-Wei YangNational Institute of Environmental Health,Chinese Center for Disease Control and Prevention,Beijing 100021,China.
Xu ZhangNational Institute of Environmental Health,Chinese Center for Disease Control and Prevention,Beijing 100021,China.
Xiao LinNational Institute of Environmental Health,Chinese Center for Disease Control and Prevention,Beijing 100021,China.
Qi SunNational Institute of Environmental Health,Chinese Center for Disease Control and Prevention,Beijing 100021,China.
Hui FuNational Institute of Environmental Health,Chinese Center for Disease Control and Prevention,Beijing 100021,China.
Yi-Fu LuNational Institute of Environmental Health,Chinese Center for Disease Control and Prevention,Beijing 100021,China.
Tian QiuNational Institute of Environmental Health,Chinese Center for Disease Control and Prevention,Beijing 100021,China.
Zhuo-Na ZhangNational Institute of Environmental Health,Chinese Center for Disease Control and Prevention,Beijing 100021,China.
Lin-Na XieNational Institute of Environmental Health,Chinese Center for Disease Control and Prevention,Beijing 100021,China.
Hai-Jing ZhangNational Institute of Environmental Health,Chinese Center for Disease Control and Prevention,Beijing 100021,China.
Miao ZhangNational Institute of Environmental Health,Chinese Center for Disease Control and Prevention,Beijing 100021,China.
Xiao-Jian HuNational Institute of Environmental Health,Chinese Center for Disease Control and Prevention,Beijing 100021,China.
Ying-Li QuNational Institute of Environmental Health,Chinese Center for Disease Control and Prevention,Beijing 100021,China.
Feng ZhaoNational Institute of Environmental Health,Chinese Center for Disease Control and Prevention,Beijing 100021,China.
Yue-Bin LyuNational Institute of Environmental Health,Chinese Center for Disease Control and Prevention,Beijing 100021,China.
Ying ZhuNational Institute of Environmental Health,Chinese Center for Disease Control and Prevention,Beijing 100021,China.
Xiao-Ming ShiChina CDC Key Laboratory of Environment and Population Health,Beijing 100021,China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The China National Human Biomonitoring Program (CNHBP) was launched in 2016. The program aims to obtain representative exposure data of environmental pollutants in the general population by carrying out field epidemiological surveys of Chinese population and monitoring of environmental pollutants in human biological tissues. This work will provide a scientific basis for the government to formulate environmental pollution prevention and control policies. One of the objectives of human biomonitoring is to provide accurate and comparable data of chemical pollutants in human biological samples. Multi-dimensional quality control measures are implemented for the targeted quantitative analysis of chemical pollutants from the analysis method, experimental blank and analysis processes. The quality control procedures are divided into two stages: (1) focusing on the verification of biomonitoring analysis method, blank screening and control in the pre-detection stage; (2) the quality control of the large-scale sample analysis process in the detection stage. Analysis methods used in CNHBP need to be validated to evaluate the performance and practicability, with emphasis on method detection limit (MDL) and method quantification limit (MQL), matrix effects, stability, and residue and dilution. Blank screening procedures are required for all monitoring indicators to identify, eliminate or reduce blank interference, and the blank value of each batch should be less than the MDL. The laboratory adopts a combination of internal and external quality control measures, the measures mainly include: (1) method validation and detection process of the 10 types of monitoring indicators all used biological matrix reference materials produced by the National Institute of Standards and Technology (NIST), European Reference Materials (ERM) and China Center for Reference Materials, to ensure the accuracy and traceability of the methods; (2) commercial quality control samples and internal quality control samples were used to evaluate the stability of the testing process for the 15 types of monitoring indicators; (3) a total of 60 monitoring indicators of the nine categories participated in the German external quality assessment scheme for analyses in biological materials (G-EQUAS) and achieved satisfactory results; (4) 15 types of monitoring indicators were tested with blind samples. Overall, multi-dimensional quality control measures provide professional support for generating high-quality biomonitoring data.

Indexed as

Biological MonitoringEnvironmental MonitoringEnvironmental PollutantsChinaHumansQuality ControlEnvironmental PollutantsChina National Human Biomonitoring Program (CNHBP)experimental blankmethod verificationquality controlreview

Identifiers

PMID40394736
PMCPMC12093211

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.