ReviewEuropean journal of medical research2025
Fluid management strategies in critically ill patients with ARDS: a narrative review.
Review in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed.
- Restrictive fluid management with early de-escalation versus usual care in critically ill patients (reduce trial): a feasibility randomized controlled trial.Critical care (London, England) · 2025Trial
- Awake Prone Positioning in Moderate ARDS: A Case Report.Clinics and practice · 2026Article
- Awake Prone Positioning in Non-Intubated Non-COVID-19 ARDS: A Comprehensive Review.Advances in respiratory medicine · 2026Review
- Ventilator-Induced Lung Liquid and Alveolar Rupture.Journal of clinical medicine · 2026Article
- [Association between adverse outcomes during hospitalization and early postnatal weight changes in term appropriate-for-gestational-age infants with early-onset sepsis].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2026Article
- The role of thoracic ultrasound in fluid management in critical care: a narrative review.Journal of thoracic disease · 2026Review
- Bridging evidence and practice: implementation science and bundled care strategies for fluid management in critically ill neonates.Frontiers in medicine · 2026Article
- Clinical characteristics and mortality outcomes of acute kidney injury following COVID-19 infection in patients with chronic kidney disease at different stages.BMC infectious diseases · 2025Article
- Review
- First Breath Matters: Out-of-Hospital Mechanical Ventilation in Patients with Traumatic Brain Injury.Journal of clinical medicine · 2025Review
- Targeting Gut-Lung Crosstalk in Acute Respiratory Distress Syndrome: Exploring the Therapeutic Potential of Fecal Microbiota Transplantation.Pathogens (Basel, Switzerland) · 2025Review
- Trajectories of cumulative fluid balance and the association with pressure injuries in ICU patients.International journal of nursing sciences · 2025Article
- A Comprehensive Review of Fluid Resuscitation Strategies in Traumatic Brain Injury.Journal of clinical medicine · 2025Review
- Acute Respiratory Distress Syndrome: Pathophysiological Insights, Subphenotypes, and Clinical Implications-A Comprehensive Review.Journal of clinical medicine · 2025Review
- Association of body mass index changes with short-term mortality risks in ICU patients with sepsis across different admission BMI states: analysis of the MIMIC-IV database.Frontiers in immunology · 2025Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hypervolemia is associated with worse outcomes in critically ill patients with acute respiratory distress syndrome (ARDS), with early positive fluid balance linked to longer intensive care unit (ICU) stays, prolonged ventilatory support, and increased mortality risk due to cardiopulmonary complications, lung edema, and extrapulmonary organ dysfunction. However, a restrictive fluid management strategy is associated with hypoperfusion and distal organ dysfunction, including acute renal failure and cognitive impairment. Indeed, fluid administration in patients with ARDS represents a challenge, as it must take into account the underlying condition, such as sepsis or acute brain injury (ABI), where optimal fluid management is a major determinant of disease outcome. In such cases, the approach to fluid administration should be individualized based on hemodynamic and clinical parameters according to the course of the disease. The strategy of "salvage, optimization, stabilization, and de-escalation" can guide fluid administration in the initial therapeutic approach, whereas negative fluid balance with the use of diuretics or renal replacement therapy (RRT) should be the goal once hemodynamic stabilization has been achieved.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.