Evidence map›Paper›PMID 40394558›Full record

ArticleBMC pulmonary medicine2025

Reduction of post-bronchoscopy pneumonia by working channel irrigation with sterile saline before diagnostic procedures.

Satoshi Nagaoka, Masaki Yamamoto, Sachi Takakura, Shunsuke Okazaki, Ryo Nakadegawa, Yuichiro Suzukawa, Anna Tanaka, Shinya Matsushita, Tatsuya Muraoka, Chihiro Maeda and 6 more

Abstract read
In one paragraph

Article in BMC pulmonary medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Satoshi NagaokaDepartment of Pulmonology, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-Ku, Yokohama, 236-0004, Japan.
Masaki YamamotoRespiratory Disease Center, Yokohama City University Medical Center, 4-57 Urafune, Minami-Ku, Yokohama, 232-0024, Japan. masakiy@yokohama-cu.ac.jp.
Sachi TakakuraRespiratory Disease Center, Yokohama City University Medical Center, 4-57 Urafune, Minami-Ku, Yokohama, 232-0024, Japan.
Shunsuke OkazakiRespiratory Disease Center, Yokohama City University Medical Center, 4-57 Urafune, Minami-Ku, Yokohama, 232-0024, Japan.
Ryo NakadegawaRespiratory Disease Center, Yokohama City University Medical Center, 4-57 Urafune, Minami-Ku, Yokohama, 232-0024, Japan.
Yuichiro SuzukawaRespiratory Disease Center, Yokohama City University Medical Center, 4-57 Urafune, Minami-Ku, Yokohama, 232-0024, Japan.
Anna TanakaRespiratory Disease Center, Yokohama City University Medical Center, 4-57 Urafune, Minami-Ku, Yokohama, 232-0024, Japan.
Shinya MatsushitaDepartment of Pulmonology, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-Ku, Yokohama, 236-0004, Japan.
Tatsuya MuraokaRespiratory Disease Center, Yokohama City University Medical Center, 4-57 Urafune, Minami-Ku, Yokohama, 232-0024, Japan.
Chihiro MaedaRespiratory Disease Center, Yokohama City University Medical Center, 4-57 Urafune, Minami-Ku, Yokohama, 232-0024, Japan.
Tomofumi HiroseRespiratory Disease Center, Yokohama City University Medical Center, 4-57 Urafune, Minami-Ku, Yokohama, 232-0024, Japan.
Kenichi SekiRespiratory Disease Center, Yokohama City University Medical Center, 4-57 Urafune, Minami-Ku, Yokohama, 232-0024, Japan.
Shuhei TeranishiRespiratory Disease Center, Yokohama City University Medical Center, 4-57 Urafune, Minami-Ku, Yokohama, 232-0024, Japan.
Ken TashiroRespiratory Disease Center, Yokohama City University Medical Center, 4-57 Urafune, Minami-Ku, Yokohama, 232-0024, Japan.
Makoto KudoRespiratory Disease Center, Yokohama City University Medical Center, 4-57 Urafune, Minami-Ku, Yokohama, 232-0024, Japan.
Takeshi KanekoDepartment of Pulmonology, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-Ku, Yokohama, 236-0004, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAfter transbronchial biopsy with flexible bronchoscopy, pneumonia sometimes occurs as a complication. The goal of our study was to determine whether irrigation of the working channel before diagnostic procedures can reduce the frequency of post-bronchoscopy pneumonia.

methodsInitially, we examined the effect of working channel irrigation with 100 mL of sterile saline to reduce the number of bacteria attached to the working channel. Subsequently, we compared the frequency of post-bronchoscopy pneumonia in patients who underwent or did not undergo working channel irrigation before bronchoscopic biopsy or lavage fluid collection.

resultsTHE MAIN

findingsA significant reduction in bacterial colonies was observed in the irrigated channel-flush samples. Of the 242 enrolled participants, 109 were in the exploratory group, whereas 133 were in the control group. The frequency of post-bronchoscopy pneumonia (PBP) was 2.8% (n = 3) and 3.8% (n = 5) in the exploratory and control groups, respectively.

conclusionsWhile the irrigation by suctioning 100 mL of sterile saline was effective in reducing the bacterial load within the channel, the reduction in pneumonia incidence did not reach statistical significance, indicating the need for further accumulation of cases.

Indexed as

BronchoscopyPneumoniaSaline SolutionTherapeutic IrrigationAdultAgedBacterial LoadBiopsyBronchoalveolar LavageBronchoalveolar Lavage FluidFemaleHumansMaleMiddle AgedSaline SolutionFlexible bronchoscopyPost-bronchoscopy feverPost-bronchoscopy pneumonia

Identifiers

PMID40394558
PMCPMC12090572

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.