Evidence map›Paper›PMID 40394537›Full record

ArticleBMC public health2025

Colorectal cancer screening blood test: awareness and willingness among a national sample of adults post-Federal and Drug Administration approval.

Mira L Katz, Holli A Loomans-Kropp, Paul L Reiter

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Emerging trends in the global burden of colorectal cancer.Nature reviews. Clinical oncology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mira L KatzCollege of Public Health, The Ohio State University, Room 212, 3650 Olentangy River Road, Columbus, OH, USA. Mira.Katz@osumc.edu.ORCID http://orcid.org/0000-0001-9791-7592
Holli A Loomans-KroppComprehensive Cancer Center, The Ohio State University, Columbus, OH, USA.
Paul L ReiterCollege of Public Health, The Ohio State University, Room 212, 3650 Olentangy River Road, Columbus, OH, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo assess awareness and willingness of average-risk adults to complete a colorectal cancer (CRC) screening blood test and evaluate test preferences for future screening.

methodsFollowing approval by the United States Food and Drug Administration, a cross-sectional online survey was conducted in September 2024 of adults ages 45-75 in the United States (n = 633). An informative statement about the new test was followed by a series of questions. Logistic regression identified correlates of participants' willingness to complete a CRC screening blood test.

resultsOnly 18.2% of participants were aware of a CRC screening blood test. Most (77.9%) were willing to get the test if free or covered by health insurance, while only 19.2% were willing if it cost $895 out of pocket. Participants were more willing to complete a free CRC screening blood test if they had a high household income (odds ratio [OR] = 5.12, 95% confidence interval [CI]: 1.63-16.13), had a routine medical check-up in the last year (OR = 2.87, CI:1.44-5.71), and were more wanting to talk to a doctor at their next medical appointment about the new test (OR = 2.55, CI: 1.92-3.37). Participants' preferred CRC screening approach for the future was the blood test every three years (53.0%), an annual stool test (31.1%), and a colonoscopy every 10 years (15.8%).

conclusionsThe blood test has the potential to increase CRC screening, as most participants were willing to complete the test if it was free or covered by health insurance. Findings can guide the development of programs that include the CRC screening blood test as an option.

Indexed as

Colorectal NeoplasmsEarly Detection of CancerHealth Knowledge, Attitudes, PracticePatient Acceptance of Health CareAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedOccult BloodSurveys and QuestionnairesUnited StatesUnited States Food and Drug AdministrationCancer early detectionCancer screeningColorectal cancerHealth surveys

Identifiers

PMID40394537
PMCPMC12090458

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.