Evidence map›Paper›PMID 40393986›Full record

ArticleNature communications2025

Human mitochondrial ferritin exhibits highly unusual iron-O

Justin M Bradley, Zinnia Bugg, Jacob Pullin, Geoffrey R Moore, Dimitri A Svistunenko, Nick E Le Brun

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Ferritin Iron Mineralisation: Route of FeAngewandte Chemie (International ed. in English) · 2026
    Article
  3. Article
  4. Cavity acidification limits ferritin iron biomineralization.Journal of inorganic biochemistry · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Novel insights of ferroptosis in atherosclerosis progression.Frontiers in cell and developmental biology · 2026
    Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Justin M BradleyCentre for Molecular and Structural Biochemistry, School of Chemistry, Pharmacy and Pharmacology, University of East Anglia, Norwich, UK.ORCID http://orcid.org/0000-0003-1635-4455
Zinnia BuggCentre for Molecular and Structural Biochemistry, School of Chemistry, Pharmacy and Pharmacology, University of East Anglia, Norwich, UK.
Jacob PullinSchool of Life Sciences, University of Essex, Colchester, UK.
Geoffrey R MooreCentre for Molecular and Structural Biochemistry, School of Chemistry, Pharmacy and Pharmacology, University of East Anglia, Norwich, UK.
Dimitri A SvistunenkoSchool of Life Sciences, University of Essex, Colchester, UK.
Nick E Le BrunCentre for Molecular and Structural Biochemistry, School of Chemistry, Pharmacy and Pharmacology, University of East Anglia, Norwich, UK. n.le-brun@uea.ac.uk.ORCID http://orcid.org/0000-0001-9780-4061

Funding

RCUK | Biotechnology and Biological Sciences Research Council (BBSRC) BB/R002363/1RCUK | Biotechnology and Biological Sciences Research Council (BBSRC) BB/R003203/1RCUK | Biotechnology and Biological Sciences Research Council (BBSRC) BB/T01802X/1
6 · The paper itself

Abstract

Ferritins are ubiquitous proteins that function in iron storage/detoxification by catalyzing the oxidation of Fe

Indexed as

CytosolFerritinsIronMitochondriaOxygenApoferritinsCeruloplasminHumansOxidation-ReductionApoferritinsCeruloplasminFerritinsIronOxygen

Identifiers

PMID40393986
PMCPMC12092714

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.