Evidence map›Paper›PMID 40393972›Full record

ReviewNature communications2025

Standardization guidelines and future trends for PET hydrolase research.

Ren Wei, Peter Westh, Gert Weber, Lars M Blank, Uwe T Bornscheuer

Abstract readReview
In one paragraph

Review in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
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  8. Journal of chemical information and modeling · 2026
    Article
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  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ren WeiDepartment of Biotechnology & Enzyme Catalysis, Institute of Biochemistry, University of Greifswald, Greifswald, Germany. ren.wei@uni-greifswald.de.ORCID http://orcid.org/0000-0003-3876-1350
Peter WesthDepartment of Biotechnology and Biomedicine, Technical University of Denmark, Lyngby, Denmark.ORCID http://orcid.org/0000-0002-6185-0637
Gert WeberMacromolecular Crystallography, Helmholtz-Zentrum Berlin für Materialien und Energie, Berlin, Germany.ORCID http://orcid.org/0000-0003-3624-1060
Lars M BlankiAMB - Institute of Applied Microbiology. ABBt - Aachen Biology and Biotechnology, BioSC, RWTH Aachen University, Aachen, Germany.ORCID http://orcid.org/0000-0003-0961-4976
Uwe T BornscheuerDepartment of Biotechnology & Enzyme Catalysis, Institute of Biochemistry, University of Greifswald, Greifswald, Germany.ORCID http://orcid.org/0000-0003-0685-2696

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enzymatic depolymerization of polyethylene terephthalate (PET) towards monomer recycling offers a green route to a circular plastic economy, with scale-up currently underway. Yet, inconsistent assessment methods hinder clear comparisons between various PET hydrolases. This Perspective aims to identify critical gaps in this dynamic research field and outline key principles for selecting and tailoring novel enzymes, such as using uniform PET samples and standardizing reaction settings that mimic industrial conditions. Applying these guidelines will improve enzyme screening efficiency, increase data reproducibility, deepen the understanding of interfacial biocatalysis, and ultimately accelerate the development of more robust and cost-effective bio-based PET recycling methods.

Indexed as

HydrolasesPolyethylene TerephthalatesBiocatalysisGuidelines as TopicReference StandardsHydrolasesPolyethylene Terephthalates

Identifiers

PMID40393972
PMCPMC12092820

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.