Evidence map›Paper›PMID 40393792›Full record

ArticleJournal of neurointerventional surgery2026

First clinical multicenter experience of the new NeVa NET 5.5 thrombectomy device.

Roland Schwab, Balázs Kis, Berki Alexandra Réka, Janos Sebestyen Gellen, Katharina Haider, Eya Khadhraoui, Sebastian Johannes Müller, Erelle Fuchs, Maximilian Thormann, Johannes Alex Rolf Pfaff and 1 more

Abstract readMulticenter Study
In one paragraph

Article in Journal of neurointerventional surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Evaluation of bail-out techniques for managing cerebral vessel perforation: An experimental study.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Roland SchwabUniversity Clinic for Neuroradiology, University Hospital Magdeburg, Magdeburg, Germany Schwab.Roland@outlook.de.ORCID http://orcid.org/0009-0008-3799-6194
Balázs KisDepartment of Radiology, Medical University of Debrecen, Debrecen, Hajdú-Bihar, Hungary.
Berki Alexandra RékaDepartment of Neurology, Medical University of Debrecen, Debrecen, Hajdú-Bihar, Hungary.
Janos Sebestyen GellenUniversity Insitute for Neuroradiology Paracelsus Medical University, University Hospital Salzburg - Christian Doppler Hospital, Salzburg, Austria.
Katharina HaiderUniversity Insitute for Neuroradiology Paracelsus Medical University, University Hospital Salzburg - Christian Doppler Hospital, Salzburg, Austria.
Eya KhadhraouiUniversity Clinic for Neuroradiology, University Hospital Magdeburg, Magdeburg, Germany.ORCID http://orcid.org/0000-0002-5433-1572
Sebastian Johannes MüllerUniversity Clinic for Neuroradiology, University Hospital Magdeburg, Magdeburg, Germany.ORCID http://orcid.org/0000-0003-2147-9797
Erelle FuchsUniversity Clinic for Neuroradiology, University Hospital Magdeburg, Magdeburg, Germany.
Maximilian ThormannDepartment of Nuclear Medicine, Charité Medical Faculty Berlin, Berlin, Germany.
Johannes Alex Rolf PfaffUniversity Insitute for Neuroradiology Paracelsus Medical University, University Hospital Salzburg - Christian Doppler Hospital, Salzburg, Austria.
Daniel BehmeUniversity Clinic for Neuroradiology, University Hospital Magdeburg, Magdeburg, Germany.ORCID http://orcid.org/0000-0002-5353-9515

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMechanical thrombectomy for the treatment of acute ischemic stroke has undergone relevant technical improvements over recent years. However, distal emboli and incomplete reperfusion after mechanical thrombectomy are still shortcomings in the care of patients with endovascular acute ischemic stroke. The NeVa NET 5.5 thrombectomy device (Vesalio, Nashville, Tennessee, USA) is the first stent retriever featuring an integrated clot micro-filtration system, aiming to enhance first pass efficacy and reduce distal embolization. This study evaluates the safety and efficacy of the NeVa NET 5.5 thrombectomy device.

methodsPatients with acute anterior circulation occlusions and vessel diameters >2 mm treated with the NeVa NET 5.5 stent retriever as a first-line approach were retrospectively included in this study. Data were collected from three European comprehensive stroke centers between October 2022 and April 2024. Patient data, occlusion details, clinical outcomes, and procedure-related parameters were analyzed.

resultsA total of 51 patients were included. The most common occlusion locations were the internal carotid artery terminus and intradural internal carotid artery (70.6%). The mean±SD clot length was 25.1±13.3 mm (range 4-50 mm). First pass reperfusion (eTICI 2b-3) was achieved in 78.5%, with a final reperfusion rate of eTICI 2b-3 in 98.1%. Distal embolization in new territories occurred in 3.9%. No device-related adverse events were reported, and procedure-related adverse events occurred in 7.6% of the overall included cases.

conclusionThe NeVa NET 5.5 stent retriever has a high first pass reperfusion rate in large vessel occlusions of the anterior circulation, with a good safety profile and low rate of distal embolization.

Indexed as

Endovascular ProceduresIschemic StrokeThrombectomyAgedAged, 80 and overFemaleHumansMaleMiddle AgedRetrospective StudiesStentsTreatment OutcomeAngiographyDeviceInterventionStrokeThrombectomy

Identifiers

PMID40393792
PMCPMC13217026

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.