Evidence map›Paper›PMID 40393778›Full record

ArticleBJGP open2025

Acne management in Norway: GP and dermatologist prescriptions (2012-2019): a nationwide overview.

Cathrine S Christiansen, Sigurd Høye, Morten Lindbaek, Jon Anders Halvorsen, Louise Emilsson

Abstract read
In one paragraph

Article in BJGP open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Cathrine S ChristiansenThe Antibiotic Centre for Primary Care, Department of General Practice, Institute of Health and Society, University of Oslo, Oslo, Norway.ORCID https://orcid.org/0009-0008-6914-9731
Sigurd HøyeThe Antibiotic Centre for Primary Care, Department of General Practice, Institute of Health and Society, University of Oslo, Oslo, Norway.ORCID https://orcid.org/0000-0003-1806-3811
Morten LindbaekThe Antibiotic Centre for Primary Care, Department of General Practice, Institute of Health and Society, University of Oslo, Oslo, Norway.
Jon Anders HalvorsenDepartment of General Practice, Institute of Health and Society, University of Oslo, Oslo, Norway.
Louise EmilssonDepartment of General Practice, Institute of Health and Society, University of Oslo, Oslo, Norway louise.emilsson@medisin.uio.no.ORCID https://orcid.org/0000-0001-9137-2800

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcne is common and associated with negative psychosocial health and risk of permanent skin alterations. GPs prescribe the main portion of antibiotics used for acne. Increased isotretinoin prescription by GPs can potentially reduce overall antibiotic use, but prescription practice and trends are unknown.

aimTo examine acne treatment in Norway and quantify prescription and initiation of isotretinoin and tetracyclines. DESIGN &

settingAn observational study linking data from health registries. Data were collected from the Norwegian Prescription Database (NorPD), the national GP claims register (KUHR database), and the Regular General Practitioner (RGP) registry.

methodAll patients aged 12-39 years who received an acne diagnosis or were prescribed acne medication in Norway 2012-2019 were included. Linear regression was used to explore time trends.

resultsIn total, 316 075 patients were included (63% female). Yearly prevalence of systemic treatment increased from 1.9 in 2012 to 2.4% in 2019; isotretinoin increased by +123%, tetracyclines by +4% as measured in defined daily doses (DDDs). Topical treatment increased by +13% as measured by number of prescriptions. GP prescription of tetracyclines decreased 11%; however, courses had a mean duration of 160 days, which is longer than the recommended 90 days, and only 26% had a co-occurring topical treatment prescription. GPs initiated 5% of isotretinoin courses in 2012, versus 10% in 2019, and 19% (

conclusionGPs reduced their prescription of tetracyclines, but our data still show potential for further improvements in prescribing practice. Increased isotretinoin prescription by GPs may lead to reduced antibiotic use and better treatment regimens for moderate-to-severe acne.

Indexed as

acne vulgarisdermatologygeneral practice

Identifiers

PMID40393778
PMCPMC12728883

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.