Evidence map›Paper›PMID 40393525›Full record

ArticleEuropean heart journal2025

Mortality in male bodybuilding athletes.

Marco Vecchiato, Andrea Ermolao, Marco Da Col, Andrea Aghi, Giampaolo Berton, Stefano Palermi, Francesca Battista, Sandro Savino, Jonathan Drezner, Alessandro Zorzi and 2 more

Abstract read
In one paragraph

Article in European heart journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Sporting Careers After ICD Implantation in Elite Athletes.Journal of cardiovascular development and disease · 2026
    Article
  10. Mortality in female bodybuilding athletes.European heart journal · 2026
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Marco VecchiatoSports and Exercise Medicine Division, Department of Medicine, University of Padova, Via Giustiniani 2, Padova 35128, Italy.ORCID 0000-0003-2395-4977
Andrea ErmolaoSports and Exercise Medicine Division, Department of Medicine, University of Padova, Via Giustiniani 2, Padova 35128, Italy.ORCID 0000-0002-0546-1514
Marco Da ColSports and Exercise Medicine Division, Department of Medicine, University of Padova, Via Giustiniani 2, Padova 35128, Italy.
Andrea AghiSports and Exercise Medicine Division, Department of Medicine, University of Padova, Via Giustiniani 2, Padova 35128, Italy.
Giampaolo BertonDivision of Cardiology, Ospedale Alto Vicentino, Santorso, Vicenza, Italy.
Stefano PalermiPublic Health Department, University of Naples Federico II, Naples, Italy.ORCID 0000-0003-1558-4857
Francesca BattistaSports and Exercise Medicine Division, Department of Medicine, University of Padova, Via Giustiniani 2, Padova 35128, Italy.ORCID 0000-0003-0760-1354
Sandro SavinoDepartment of Medicine, University of Padova, Padova, Italy.
Jonathan DreznerDepartment of Family Medicine, University of Washington, Seattle, Washington, USA.
Alessandro ZorziDepartment of Cardio-Thoraco-Vascular Sciences and Public Health, University of Padova, Padova, Italy.
Josef NiebauerUniversity Institute of Sports Medicine, Prevention and Rehabilitation, Paracelsus Medical University, Salzburg, Austria.ORCID 0000-0002-2811-9041
Daniel NeunhaeusererSports and Exercise Medicine Division, Department of Medicine, University of Padova, Via Giustiniani 2, Padova 35128, Italy.ORCID 0000-0001-9775-4260

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsPremature deaths of bodybuilders have raised questions about the safety and associated risks of this discipline. The main objective of this study was to analyse mortality risk in a large international population of bodybuilders.

methodsMale athletes who performed International Federation of Bodybuilding and Fitness (IFBB) competitions between 2005 and 2020 were identified and classified according to age, division and level. A standardized web-search, tailored to detect deaths, was performed for each athlete using specific keywords, with follow-up through July 2023. Mortality rates have been calculated both as the overall incidence rate during the monitored period as well as the annual incidence rate of those who participated in at least one competition within the previous year, i.e. currently competing athletes.

resultsA total of 20 286 athletes competing in 730 IFBB events were identified with an average follow-up of 8.1 ± 3.8 years (i.e. 190 211 athlete-years of surveillance). During the study period, 121 deaths were identified: 73 were considered sudden deaths, of which 46 were classified as sudden cardiac deaths (SCD), including 11 currently competing athletes (mean age 34.7 ± 6.1 years). The incidence of SCD in currently competing athletes was 32.83 cases per 100 000 athlete-years. Available autopsies of SCD cases consistently showed cardiomegaly and ventricular hypertrophy. Professional bodybuilders had a higher risk of SCD than amateurs (HR 5.23 [3.58-7.64]).

conclusionsThe results of this study should alert the bodybuilding and medical communities to the need for improved preventive measures to promote safer sports participation.

Indexed as

AthletesDeath, Sudden, CardiacWeight LiftingAdultHumansIncidenceMaleRisk FactorsYoung AdultAnabolic steroidsBodybuilderDopingPre-participation screeningPreventionSudden cardiac deathSudden death

Identifiers

PMID40393525
PMCPMC12342505

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.