Evidence map›Paper›PMID 40392850›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Inflammatory cytokine upd3 induces axon length-dependent synapse removal by glia.

Federico Marcello Tenedini, Chang Yin, Jessica M Huang, Neena Dhiman, Peter Soba, Jay Z Parrish

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Federico Marcello Tenedini *Department of Biology, University of Washington, Seattle, WA 98195.ORCID 0000-0003-2274-0424
Chang Yin *Department of Biology, University of Washington, Seattle, WA 98195.
Jessica M HuangDepartment of Biology, University of Washington, Seattle, WA 98195.ORCID 0009-0003-6452-3054
Neena DhimanInstitute of Physiology and Pathophysiology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany.ORCID 0009-0002-5643-7810
Peter SobaInstitute of Physiology and Pathophysiology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany.
Jay Z ParrishDepartment of Biology, University of Washington, Seattle, WA 98195.ORCID 0000-0002-0656-9148

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Structural and functional coupling of epidermis to somatosensory neurons in DrosophilaR01NS076614 · NINDS · UNIVERSITY OF WASHINGTON · PI BAUTISTA, DIANA MICHELE, PARRISH, JAY Z · 2011 to 2023
$4.2M
Identification of proteins that structurally couple epidermal cells to somatosensory neuronsR21NS125795 · NINDS · UNIVERSITY OF WASHINGTON · PI PARRISH, JAY Z, ROGERS, STEPHEN · 2021 to 2021
$442k
Deutsche Forschungsgemeinschaft (DFG) SO 1337/2-2Deutsche Forschungsgemeinschaft (DFG) SO1337/6-1Deutsche Forschungsgemeinschaft (DFG) SO 1337/7-1HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS) R21NS125795NIH HHS P40 OD018537NINDS NIH HHS R01 NS076614NINDS NIH HHS R21 NS125795Scan Design Foundation N/AUW School of Medicine Diabetes Pilot Award N/AWeill Neurohub N/A
6 · The paper itself

Abstract

Many neurodegenerative disorders (NDDs) preferentially affect neurons with long or complex axonal arbors but the cellular and molecular bases for neurite length-dependent vulnerability of neurons to degeneration is largely unknown. Using

Indexed as

AxonsCytokinesDrosophila ProteinsNeurogliaSynapsesAnimalsDrosophilaDrosophila melanogasterHumansNeurodegenerative DiseasesPhagocytosisSensory Receptor CellsSignal TransductionCytokinesDrosophila Proteinsaxoncytokineglianeurodegenerationneuron

Identifiers

PMID40392850
PMCPMC12130839

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.