Evidence map›Paper›PMID 40392846›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Pattern formation along signaling gradients driven by active droplet behavior of cell swarms.

Hugh Z Ford, Giulia L Celora, Elizabeth R Westbrook, Mohit P Dalwadi, Benjamin J Walker, Hella Baumann, Cornelis J Weijer, Philip Pearce, Jonathan R Chubb

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. What is active wetting?The European physical journal. E, Soft matter · 2026
    Review
  3. Article
  4. Pattern formation along signaling gradients driven by active droplet behavior of cell swarms.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hugh Z Ford *Institute for the Physics of Living Systems, University College London, United Kingdom.ORCID 0000-0002-0457-7224
Giulia L Celora *Institute for the Physics of Living Systems, University College London, United Kingdom.ORCID 0000-0001-5161-6292
Elizabeth R WestbrookInstitute for the Physics of Living Systems, University College London, United Kingdom.ORCID 0000-0003-1881-5534
Mohit P DalwadiInstitute for the Physics of Living Systems, University College London, United Kingdom.ORCID 0000-0001-5017-2116
Benjamin J WalkerInstitute for the Physics of Living Systems, University College London, United Kingdom.ORCID 0000-0003-0853-267X
Hella BaumannIntelligent Imaging Innovations Ltd, 17 Westbourne Studios, London W10 5JJ, United Kingdom.
Cornelis J WeijerDivision of Molecular, Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dundee DD1 5EH, United Kingdom.ORCID 0000-0003-2192-8150
Philip PearceInstitute for the Physics of Living Systems, University College London, United Kingdom.ORCID 0000-0001-5788-3826
Jonathan R ChubbInstitute for the Physics of Living Systems, University College London, United Kingdom.ORCID 0000-0001-6898-9765

Funding

UK Research and Innovation (UKRI) MR/V022385/1UKRI | Biotechnology and Biological Sciences Research Council (BBSRC) BB/R000441/1UKRI | Engineering and Physical Sciences Research Council (EPSRC) EP/W032317/1UKRI | Engineering and Physical Sciences Research Council (EPSRC) EP/W524335/1Wellcome TrustWellcome Trust (WT) 226655/Z/22/Z
6 · The paper itself

Abstract

Gradients of extracellular signals organize cells in tissues. Although there are several models for how gradients can pattern cell behavior, it is not clear how cells react to gradients when the population is undergoing 3D morphogenesis, in which cell-cell and cell-signal interactions are continually changing.

Indexed as

DictyosteliumSignal TransductionCell DifferentiationCell MovementModels, BiologicalMorphogenesisactive dropletchemotaxispattern formationsignaling gradientstissue fluidity

Identifiers

PMID40392846
PMCPMC12130873

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.