Evidence map›Paper›PMID 40392845›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Stathmin-2 enhances motor axon regeneration after injury independent of its binding to tubulin.

Melinda S Beccari, Olatz Arnold-Garcia, Michael W Baughn, Jonathan W Artates, Melissa McAlonis-Downes, Jaisen Lim, Dulce Fernanda Leyva-Cázares, Hugo Isaac Rubio-Lara, Andrea Ramirez-Rodriguez, Carol N Bernal-Buenrostro and 9 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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  13. Stathmin-2 enhances motor axon regeneration after injury independent of its binding to tubulin.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Melinda S BeccariDepartment of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093.
Olatz Arnold-GarciaDepartment of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093.
Michael W BaughnDepartment of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093.
Jonathan W ArtatesDepartment of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093.
Melissa McAlonis-DownesDepartment of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093.
Jaisen LimDepartment of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093.
Dulce Fernanda Leyva-CázaresDepartment of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093.
Hugo Isaac Rubio-LaraDepartment of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093.
Andrea Ramirez-RodriguezDepartment of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093.
Carol N Bernal-BuenrostroDepartment of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093.
Brian Murgia-BayDepartment of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093.
Carolina K RangelPrinses Maxima Centrum voor Kinderoncologie, Utrecht 3584 CS, The Netherlands.
Dong Hyun KimDepartment of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093.
Ze'ev MelamedDepartment of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093.
Cathleen M LutzRare Disease Translational Center, The Jackson Laboratory, Bar Harbor, ME 04609.ORCID 0000-0003-2502-1900
Clotilde Lagier-TourenneDepartment of Neurology, Sean M. Healey and AMG Center for ALS, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114.ORCID 0000-0002-3058-8322
Kevin D CorbettDepartment of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093.ORCID 0000-0001-5854-2388
Jone López-ErauskinDepartment of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093.
Don W ClevelandDepartment of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093.

Funding

U of Calif, San Diego Neuroscience Microscopy ImagingP30NS047101 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GLEESON, JOSEPH G, ZHENG, BINHAI · 2003 to 2022
$9.0M
Training Program in Basic Clinical GeneticsT32GM008666 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HAMILTON, BRUCE A · 1998 to 2021
$8.6M
Determining stathmin-2 function and potential as a therapeutic target in ALS/FTDR01NS112503 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CLEVELAND, DON W, LAGIER-TOURENNE, CLOTILDE · 2020 to 2024
$4.1M
Mechanism of stathmin-2-dependent axon maintenance, regeneration, and functionR37NS112503 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CLEVELAND, DON W, LAGIER-TOURENNE, CLOTILDE · 2025 to 2025
$3.1M
Molecular mechanisms of nucleic acid recognition and maintenance in meiosis and innate immunityR35GM144121 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Kevin Daniel Corbett · 2022 to 2026
$2.7M
In vivo modelling and therapy development for stathmin-2 loss in TDP-43 proteinopathiesRF1NS124203 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI CLEVELAND, DON W, LAGIER-TOURENNE, CLOTILDE · 2021 to 2021
$2.5M
Multidisciplinary training in basic and translational Alzheimer's disease researchT32AG066596 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BREWER, JAMES B · 2020 to 2024
$2.2M
In vivo modelling and therapy development for stathmin-2 loss in TDP-43 proteinopathiesR01NS124203 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI CLEVELAND, DON W, LAGIER-TOURENNE, CLOTILDE · 2024 to 2025
$1.6M
HHS | NIH | National Institute of General Medical Sciences (NIGMS) R35GM144121HHS | NIH | National Institute of General Medical Sciences (NIGMS) T32GM008666HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS) P30NS047101HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS) R01NS112503HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS) RF1NS124203HHS | NIH | National Institute on Aging (NIA) T32AG066596Muscular Dystrophy Association (MDA) N/ANIA NIH HHS T32 AG066596NIGMS NIH HHS R35 GM144121NIGMS NIH HHS T32 GM008666NINDS NIH HHS P30 NS047101NINDS NIH HHS R01 NS112503NINDS NIH HHS R01 NS124203NINDS NIH HHS R37 NS112503NINDS NIH HHS RF1 NS124203NOMIS Stiftung (NOMIS Foundation) N/A
6 · The paper itself

Abstract

Stathmin-2 (also known as

Indexed as

AxonsMotor NeuronsNerve RegenerationStathminTubulinAnimalsHumansMiceMice, KnockoutMicrotubulesNeuromuscular JunctionProtein BindingStathminTubulinaxon regenerationmicrotubulesNMNAT2SCG10STMN2

Identifiers

PMID40392845
PMCPMC12130871

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.