Evidence map›Paper›PMID 40392716›Full record

Trial reportThe Journal of clinical psychiatry2025

Results of a Randomized Controlled Trial Examining the Efficacy of Intranasal Oxytocin to Enhance Alcohol Behavioral Couple Therapy.

Julianne C Flanagan, Paul J Nietert, Barbara S McCrady, Stacey Sellers, Anjinetta Yates-Johnson, Sarah T Giff, Shannon R Forkus

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in The Journal of clinical psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Psychosocial Interventions for Alcohol Use Disorder: A Review of Efficacy, Mechanisms, and Clinical Implications.Medical science monitor : international medical journal of experimental and clinical research · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Julianne C FlanaganDepartment of Psychiatry and Behavioral Sciences, College of Medicine, Medical University of South Carolina, Charleston, South Carolina.
Paul J NietertDepartment of Public Health Sciences, College of Medicine, Medical University of South Carolina, Charleston, South Carolina.
Barbara S McCradyDepartment of Psychology and Center on Alcohol, Substance Use, and Addictions, University of New Mexico, Albuquerque, New Mexico.
Stacey SellersDepartment of Psychiatry and Behavioral Sciences, College of Medicine, Medical University of South Carolina, Charleston, South Carolina.
Anjinetta Yates-JohnsonDepartment of Psychiatry and Behavioral Sciences, College of Medicine, Medical University of South Carolina, Charleston, South Carolina.
Sarah T GiffDepartment of Psychiatry and Behavioral Sciences, College of Medicine, Medical University of South Carolina, Charleston, South Carolina.
Shannon R ForkusDepartment of Psychiatry and Behavioral Sciences, College of Medicine, Medical University of South Carolina, Charleston, South Carolina.

Funding

South Carolina Clinical & Translational Research Institute (SCTR)UL1TR001450 · NCATS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T., FLUME, PATRICK A · 2015 to 2024
$41.1M
Oxytocin to Enhance Alcohol Behavioral Couple TherapyR01AA027212 · NIAAA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI FLANAGAN, JULIANNE CHRISTINA · 2018 to 2022
$2.7M
Advancing Couple and Family Alcohol Treatment through Patient-Oriented Research and MentorshipK24AA030825 · NIAAA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI JULIANNE Christina Flanagan · 2023 to 2026
$767k
The effect of self-compassion on integrated treatment outcomes among veterans with co-occurring AUD and PTSD.F32AA031161 · NIAAA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI FORKUS, SHANNON · 2023 to 2024
$148k
NCATS NIH HHS UL1 TR001450NIAAA NIH HHS F32 AA031161NIAAA NIH HHS K24 AA030825NIAAA NIH HHS R01 AA027212
6 · The paper itself

Abstract

Indexed as

AlcoholismCouples TherapyOxytocinAdministration, IntranasalAdultDouble-Blind MethodFemaleHumansMaleMiddle AgedTreatment OutcomeOxytocin

Identifiers

PMID40392716
PMCPMC12766540

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.