Evidence map›Paper›PMID 40392450›Full record

ArticleJournal of fluorescence2025

Anionic Surfactant-Triggered Excimer Emission from Dipyrene-Based Amphiphilic Dyes for Wash-Free Cell Membrane Imaging.

Yongling Zheng, Bailin Guo, Enju Wang, Bingxin Lei

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of fluorescence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yongling ZhengKey Laboratory of Tropical Medicinal Resource Chemistry of Ministry of Education, Key Laboratory of Tropical Medicinal Plant Chemistry of Hainan Province, College of Chemistry & Chemical Engineering, Hainan Normal University, Haikou, 571158, P. R. China.
Bailin GuoKey Laboratory of Tropical Medicinal Resource Chemistry of Ministry of Education, Key Laboratory of Tropical Medicinal Plant Chemistry of Hainan Province, College of Chemistry & Chemical Engineering, Hainan Normal University, Haikou, 571158, P. R. China.
Enju WangKey Laboratory of Tropical Medicinal Resource Chemistry of Ministry of Education, Key Laboratory of Tropical Medicinal Plant Chemistry of Hainan Province, College of Chemistry & Chemical Engineering, Hainan Normal University, Haikou, 571158, P. R. China. enjuwang@163.com.
Bingxin LeiGuangxi Key Laboratory of Advanced Structural Materials and Carbon Neutralization, Guangxi Colleges and Universities Key Laboratory of Eco-friendly Materials and Eco-restoration, Guangxi Minzu University, Nanning, 530105, P. R. China. bingxinlei110@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Compared to monomer emission, excimer emission usually exhibits red-shifted, broadened, and large Stokes-shifted characteristics, which offer distinct advantages in biological imaging. In this work, we developed a rational design strategy for excimer-based cell membrane fluorescent probes, and on this basis, three fluorescent dyes (BPVP-C3, BPVP-C5 and BPVP-C8) exhibiting tunable excimer/monomer emission were obtained by covalent coupling of two pyrene units. In sodium dodecyl sulfate micelles, these fluorophores show bright excimer emission, whereas in dilute aqueous solutions, they emit monomer-dominated fluorescence. We proposed that the anionic micellar environment promotes intramolecular excimer formation between coupled pyrene units due to its balanced amphiphilicity, while these dye molecules can freely swing in dilute aqueous solution. Among them, BPVP-C8 exhibited optimal excimer-monomer switching property. Leveraging this environment-responsive dual-emission, it was explored as a wash-free cell membrane probe for simultaneous dual-channel (green and red) imaging.

Indexed as

Cell MembraneFluorescent DyesOptical ImagingPyrenesSurface-Active AgentsAnionsHumansMicellesAnionsFluorescent DyesMicellesPyrenesSurface-Active AgentsAnionic surfactantCell membrane imagingExcimerFolded conformationPyrene

Identifiers

PMID40392450

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.