ArticleMolecular and cellular biochemistry2025
Single cell transcription revealing key transcription factors in embryonic kidney development.
Article in Molecular and cellular biochemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Dissecting Normal and Abnormal Human Kidney Development Using Multiomics.Journal of the American Society of Nephrology : JASN · 2026Review
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Authors and funding
14 authors.
Funding
Abstract
The development of the kidney is a complex process involving the differentiation of renal progenitor cells into various specialized cell types, including renal tubular epithelial cells and podocytes. Understanding the molecular mechanisms that govern this differentiation process is crucial for unraveling the intricacies of kidney development. Recent advances in single-cell RNA sequencing technology have enabled researchers to explore the heterogeneity of renal progenitor cells at an unprecedented resolution, offering new insights into the distinct subpopulations and transcriptional landscapes within these cells. Our analysis revealed the presence of distinct subpopulations within renal progenitor cells. Furthermore, we identified key transcription factors that are crucial for the differentiation of these progenitors into renal tubular epithelial cells and podocytes. These findings provide new insights into the molecular mechanisms of kidney development, highlighting the role of specific transcription factors in the differentiation of renal progenitor cells. Although further research is needed to fully validate these findings and their therapeutic potential, this study provides a valuable foundation for future exploration of kidney regeneration strategies.
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