ArticleVeterinary research communications2025
Use of cold atmospheric plasma (CAP) for the control of gingival inflammation in a rabbit (Oryctolagus cuniculus) with progressive syndrome of acquired dental disease (PSADD): case report.
Article in Veterinary research communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Progressive syndrome of acquired dental disease (PSADD) is common in domestic rabbits and is often associated with chronic gingivitis, which compromises quality of life. Conventional treatment involves prolonged use of antimicrobials and anti-inflammatories, which may cause resistance and adverse effects. Cold atmospheric plasma (CAP) has antimicrobial, anti-inflammatory and regenerative properties, suggesting its therapeutic potential. This pilot study evaluated the effects of CAP as a complementary treatment for gingivitis associated with PSADD in a domestic rabbit. Two applications of the plasma jet were performed on the gingiva of the incisors, with an interval of seven days. The CAP was generated with helium gas at 2 L/min, 1.2 W power, 1.08 mA current and 10 Hz frequency, with application time of 30s/cm² of the affected area. Efficacy was assessed by clinical and histopathological scores before and after the intervention. The results indicated a significant reduction in gingival hyperemia and edema, in addition to the inhibition of the inflammatory infiltrate and regeneration of the lamina propria. After treatment, the patient also presented weight gain of 100 g, suggesting improvement in general well-being. These findings reinforce the potential of CAP as a complementary approach in PSADD, reducing the need for prolonged pharmacological therapies and promoting tissue regeneration.
Indexed as
Identifiers
40392416What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.