ArticleDiscover oncology2025
Interaction between Dectin-1 gene polymorphisms and low weight on the risk of invasive pulmonary aspergillosis in patients with lung cancer undergoing surgery.
Article in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Synergistic effects of S100 calcium-binding protein A12 combined with Pentraxin 3 in invasive pulmonary aspergillosis and their clinical application prospects.Frontiers in cellular and infection microbiology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The aim of this study was to investigate the impact of four single nucleotide polymorphisms (SNPs) within the Dectin-1 gene, the interaction between SNPs of the Dectin-1 gene and the low weight on susceptibility to invasive pulmonary aspergillosis (IPA) in patients with lung cancer undergoing surgery. Logistic regression was used to test the relationship between four SNPs of the Dectin-1 gene and IPA susceptibility. The generalized multifactor dimensionality reduction (GMDR) model was used to assess the interaction between SNPs of Dectin-1 gene and low weight. We found that both the rs3901533-TT and the rs3901533-TT or GT genotype were associated with an increased risk of IPA, the adjusted ORs (95% CI) were 1.98 (1.37-2.62) (TT vs. GG) and 1.43 (1.10-1.81) (GT+TT vs. GG), respectively. We also found that rs7309123-GG and rs7309123-GG+CG genotypes were associated with an increased risk of IPA, adjusted OR (95% CI) were 2.06 (1.43-2.71) (GG vs. CC), 1.63 (1.15-2.12) (CG+GG vs. CC), respectively. GMDR model found a statistically significant two-dimensional model combination (including rs3901533 and low weight). The participants with rs3901533-GT or TT genotype and low weight had the highest risk of IPA, compared to participants with rs3901533-GG genotype and without low weight, OR (95% CI) was 3.24 (1.68-4.92) (p < 0.001). In conclusion, rs3901533 and rs7309123 of Dectin-1 gene, the interaction between rs3901533 and low weight were correlated with increased risk of IPA in patients with lung cancer undergoing surgery.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.