Evidence map›Paper›PMID 40392067›Full record

ReviewJournal of medical primatology2025

The Owl Monkey (Aotus spp.) as an Animal Research Model. Part 2: Physiology, Immunology, Reproduction, and Environmental Requirements.

Alfonso S Gozalo, William R Elkins

Abstract readReview
In one paragraph

Review in Journal of medical primatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Alfonso S GozaloComparative Medicine Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.ORCID https://orcid.org/0000-0001-5445-7565
William R ElkinsComparative Medicine Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.

Funding

Intramural NIH HHS Z99 AI999999Intramural Research Program of the National Institutes of HealthNational Institute of Allergy and Infectious Diseases
6 · The paper itself

Abstract

Owl monkeys (Aotus spp.) are the only nocturnal simian primates, and as such, they are very different from other nonhuman primate species. Despite owl monkeys being used as an animal model to study malaria for over 50 years, there is not much information about their requirements in captivity compared to other primate species commonly used in biomedical research. Adaptation to a nocturnal life implies changes in the biology of the species, changes that are not seen in diurnal nonhuman primates. Here we briefly review the physiology, immunology, reproduction, and environmental requirements of the owl monkey in hopes it will provide guidance to animal care personnel and investigators when designing housing and managing this invaluable species in captivity.

Indexed as

AotidaeModels, AnimalReproductionAnimalsEnvironmentHousing, AnimalAotidaehusbandrymalarianight monkey

Identifiers

PMID40392067
PMCPMC12186666

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.