ArticleVeterinary medicine and science2025
An Unusual Encounter: Mycobacterium Paratuberculosis Infection in Wild Sheep.
Article in Veterinary medicine and science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- East AsianJournal of veterinary science · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundJohne's disease (JD), paratuberculosis, is a chronic and debilitating intestinal disease affecting ruminants, caused by Mycobacterium avium subspecies paratuberculosis (MAP). Although JD has been extensively studied in domestic livestock, its prevalence and impact on wildlife in Iran, particularly among wild sheep, remain underexplored. CASE DESCRIPTION: This study presents the first documented cases of JD in two free-ranging, 3-year-old Isfahan wild sheep (Ovis orientalis isphahanica), which exhibited weight loss, hyperthermia and neurological symptoms, including paddling movements. The sheep developed acute watery diarrhoea and severe emaciation, culminating in death. Diagnostic evaluations-including haematology, clinical chemistry, gross pathology, histopathology and microbiology-revealed hypoproteinaemia, hypoalbuminaemia, regenerative anaemia and leukocytosis, all indicative of chronic infection. Necropsy findings highlighted pulmonary congestion, mesenteric lymphadenopathy and gastrointestinal thickening, whereas histopathology showed epithelioid macrophage infiltration and substantial intestinal oedema. Molecular analysis via endpoint polymerase chain reaction (PCR) confirmed the presence of MAP DNA in tissue samples.
conclusionsThis report is the first to document JD in wild sheep in Iran, underscoring the potential role of MAP as a disease reservoir in wildlife. The findings emphasize the need for epidemiological surveillance of JD in wildlife and the importance of understanding its potential cross-species transmission risks.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.