Evidence map›Paper›PMID 40391936›Full record

ArticleAntimicrobial agents and chemotherapy2025

The novel polymyxin analogue SPR206 exhibits higher activity than colistin against both colistin-susceptible and colistin-resistant strains of

Michelle Outeda-García, Andrea Garcia-Pose, Paula Guijarro-Sánchez, Arianna Rodríguez-Coello, Gabriela Alejandra Báez-Barroso, Romina Maceiras, Isaac Alonso-García, Jorge Arca-Suárez, Juan C Vázquez-Ucha, German Bou and 2 more

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Bacterial cell envelope-targeting antibiotics.Nature reviews. Microbiology · 2026
    Review
  3. Review
  4. Advances of Antimicrobial Peptides in the Treatment of Multidrug-Resistant Bacteria.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Michelle Outeda-García *Microbiology Service and Institute for Biomedical Research A Coruña (INIBIC), Complexo Hospitalario Universitario A Coruña (CHUAC), A Coruña, Spain.ORCID 0000-0002-6737-0239
Andrea Garcia-Pose *Microbiology Service and Institute for Biomedical Research A Coruña (INIBIC), Complexo Hospitalario Universitario A Coruña (CHUAC), A Coruña, Spain.ORCID 0009-0005-1156-4199
Paula Guijarro-SánchezMicrobiology Service and Institute for Biomedical Research A Coruña (INIBIC), Complexo Hospitalario Universitario A Coruña (CHUAC), A Coruña, Spain.
Arianna Rodríguez-CoelloMicrobiology Service and Institute for Biomedical Research A Coruña (INIBIC), Complexo Hospitalario Universitario A Coruña (CHUAC), A Coruña, Spain.
Gabriela Alejandra Báez-BarrosoMicrobiology Service and Institute for Biomedical Research A Coruña (INIBIC), Complexo Hospitalario Universitario A Coruña (CHUAC), A Coruña, Spain.
Romina MaceirasMicrobiology Service and Institute for Biomedical Research A Coruña (INIBIC), Complexo Hospitalario Universitario A Coruña (CHUAC), A Coruña, Spain.
Isaac Alonso-GarcíaMicrobiology Service and Institute for Biomedical Research A Coruña (INIBIC), Complexo Hospitalario Universitario A Coruña (CHUAC), A Coruña, Spain.
Jorge Arca-SuárezMicrobiology Service and Institute for Biomedical Research A Coruña (INIBIC), Complexo Hospitalario Universitario A Coruña (CHUAC), A Coruña, Spain.ORCID 0000-0002-4248-503X
Juan C Vázquez-UchaMicrobiology Service and Institute for Biomedical Research A Coruña (INIBIC), Complexo Hospitalario Universitario A Coruña (CHUAC), A Coruña, Spain.ORCID 0000-0003-4949-0779
German Bou *Microbiology Service and Institute for Biomedical Research A Coruña (INIBIC), Complexo Hospitalario Universitario A Coruña (CHUAC), A Coruña, Spain.ORCID 0000-0001-8837-0062
Alejandro Beceiro *Microbiology Service and Institute for Biomedical Research A Coruña (INIBIC), Complexo Hospitalario Universitario A Coruña (CHUAC), A Coruña, Spain.ORCID 0000-0002-6340-7815
Spanish National Acinetobacter spp. 2020 Study Group

Funding

Axencia Galega de Innovación IN606A 2021/021Axencia Galega de Innovación IN606A 20223/023Axencia Galega de Innovación IN606A 2024/033Axencia Galega de Innovación IN606B 2022/009Axencia Galega de Innovación IN607A 2020/05Axencia Galega de Innovación IN607D 2021/12Axencia Galega de Innovación IN607D 2024/008MEC | Instituto de Salud Carlos III (ISCIII) JR23/00036MEC | Instituto de Salud Carlos III (ISCIII) PI20/01212, PI23/00851MEC | Instituto de Salud Carlos III (ISCIII) PI21/00704,CB21/13/00055MEC | Instituto de Salud Carlos III (ISCIII) PI22/01212, JR21/00026
6 · The paper itself

Abstract

Colistin resistance is increasing globally and complicates treatments of

Indexed as

Acinetobacter baumanniiAnti-Bacterial AgentsColistinPolymyxinsAcinetobacter InfectionsBacterial ProteinsDrug Resistance, Multiple, BacterialHumansMicrobial Sensitivity TestsMutationAnti-Bacterial AgentsBacterial ProteinsColistinPolymyxinsAcinetobacter baumanniiantimicrobial resistancecolistinSPR206

Identifiers

PMID40391936
PMCPMC12217451

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.